A Single-Arm Clinical Trial of Percutaneous Splenic Ablation Combined With Splenic Artery Occlusion for Secondary Hypersplenism.

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorTianjin Medical University Cancer Institute and Hospital

About this trial

This study assesses the effectiveness of microwave ablation of the spleen in conjunction with splenic artery occlusion for treating secondary hypersplenism.

Eligibility criteria

Qualifiers

1. written informed consent signed prior to enrolment 2. age > 18 years, both sexes 3.Patients with severe hypersplenism secondary to cirrhosis with clinical diagnosis, White blood cells <3×109/L, and/or platelet <50×109/L 4.Patients who have been repeatedly given drugs to raise white blood cells and platelets in clinical practice have poor effect 5.Mental problems such as clinical symptoms or anxiety in patients require interventional treatment for hypersplenism

Disqualifiers

Patients with any of the following are not eligible for enrollment in this study

Coagulopathy or other blood disorders

Recent use of anticoagulant drugs

Severe hypertension and cardiac insufficiency

Trial design

Treatments tested in this trial

  • microwave ablation of the spleen
  • Splenic artery balloon implantation

Treatment groups

35 Participants
are divided into 1 treatment group