A Study Comparing Eggshell Based and Gold Standard Materials to Heal Deep Tooth Damage in Adult Molars

ConditionIndirect Pulp Cap

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-40

SponsorUniversity of Health Sciences Lahore

About this trial

This clinical trial will evaluate the effectiveness of eggshell-derived calcium hydroxyapatite compared to calcium hydroxide as indirect pulp capping agent in permanent teeth. A total of 54 teeth from healthy individuals aged 18 to 40 years will be randomly allocated into two groups:

Group A (experimental) treated with eggshell-derived calcium hydroxyapatite. Group B (control) treated with calcium hydroxide.

After caries removal the assigned pulp capping agent will be applied, and the teeth will be restored. Clinical and radiographic evaluations will be performed at 1 and 3 months to assess pulp vitality, symptom-free status, and periapical health.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Teeth with symptoms of reversible pulpitis.

Teeth that show positive response on electric pulp testing (EPT).

Teeth with caries penetrating up to three-quarters (¾) of dentine without pulp involvement.

Healthy cooperative patients of both sexes between 18 to 40 years of age.

Disqualifiers

Necrosed Teeth with radiolucency in the periapical and furcation regions.

Tooth with internal and external root resorption.

Periodontally compromised tooth. (BPE score 3 and above)

Physically and mentally handicapped patients. (ASA score 3 and above)

Trial design

Design model

Parallel

Treatments tested in this trial

eggshell-derived calcium hydroxyapatite
Biological/Vaccine
eggshell-derived calcium hydroxyapatite will be placed as an indirect pulp capping material after chemo-mechanical caries removal and before final restoration with glass ionomer cement and composite resin.
Calcium hydroxide
Biological/Vaccine
Calcium hydroxide will be placed as an indirect pulp capping material after chemo-mechanical caries removal and before final restoration with glass ionomer cement and composite resin.

Treatment groups

54 Participants

are divided into 2 treatment groups

Group A: eggshell-derived calcium hydroxyapatiteExperimental treatment 1 intervention

Group B: Calcium hydroxideActive comparator 1 intervention

Trial outcomes

Primary outcomes

clinical symptoms (pain on percussion, tooth mobility) and radiographic evaluation

Evaluates absence of pain and pathological mobility, Measures dentine bridge thickness and absence of periapical pathology.

Time frame

3 months

Secondary outcomes

restoration success, post operative sensitivity

Records patient-reported sensitivity and discomfort

Time frame

baseline to seven days

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Health Sciences Lahore

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: