A Study for Dynamic Prediction Model of Breast Cancer Bone Metastases

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age20-70
SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences

About this trial

The purpose of this study is to identify the risk factors of bone metastasis in breast cancer patients so as to develop a dynamic prediction model using real world clinical data. The multicenter data will be retrospectively collected, and the clinical characteristics related to bone metastasis will be analyzed.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients diagnosed with breast cancer by histopathology;

Age between 20 and 70 years old;

The first diagnosis time is between 2010 and 2020;

Complete diagnosis and treatment information, including basic information, breast cancer diagnosis, surgery, recurrence diagnosis data (including the diagnosis of the metastasis sites), anti-tumor treatment data, bone health and bone metastasis-related diagnosis and treatment data, etc.;

Disqualifiers

Missing important basic information (including initial and recurrent pathology, stage, pathological grade and time, surgery time, and drug treatment);

With distant metastasis at the initial diagnosis;

Patients with autoimmune diseases or aggressive viral infections (such as HIV or hepatitis);

Other malignant tumors;

Trial population

3500 breast cancer patients diagnosed between 2010 and 2020.

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

  • Breast cancer patients with bone metastasis

    Other intervention

    This study is an observational study

  • Breast cancer patients without bone metastasis

    Other intervention

    This study is an observational study

Treatment groups

3,500 Participants
are divided into 2 treatment groups
Group A: Breast cancer patients with bone metastasis1 intervention
Group B: Breast cancer patients without bone metastasis1 intervention

Trial outcomes

Primary outcomes

1

To identify the risk factors and develop a prediction model for bone metastasis in breast cancer patients

The correlation between clinical characteristics and bone metastasis, and the accuracy of prediction model

Time frame
60 months

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

This trial is not recruiting at the moment. You can still explore other options: