Health TrialsbyHealthPanel

A Study Of Acute Decompensated Heart Failure

ConditionAcute Decompensated Heart Failure
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMayo Clinic

About this trial

The purpose of this study is to examine shorter hospitalization length as well as a reduced rates of recurrent heart failure hospitalization compared to current standard of care in Acute Decompensated Heart Failure. A 1-day reduction in hospital length of stay in unblinded subjects receiving daily HF-FOCUS examinations compared to a blinded standard of care arm.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Subjects ≥18 years of age

Admitted to St. Mary's Hospital Cardiology Progressive Care Unit (Cardiology 1-5 teams)

Acute systolic heart failure

Acute on chronic systolic heart failure

Disqualifiers

Subjects <18 years of age

Unable to provide informed consent.

Unwilling to undergo daily lung ultrasound examinations.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Lung Ultrasound

    Diagnostic test

    Patients will undergo lung ultrasound assessments at hospital admission, daily throughout admission, and at hospital discharge.

Treatment groups

500 Participants
are divided into 2 treatment groups
Group A: Group 1Active comparator 1 intervention
Group B: Group 2Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Number of days in the hospital

The number of days a patient is in the hospital will be determined by the day of admission and day of discharge. The day of discharge will be defined as when the consultant physician states that the patient is medically ready for discharge from the hospital.

Time frame
Baseline

Secondary outcomes

1

Number of re-hospitalized patients

Number of patients re-hospitalized will be determined by the number of patients admitted to the hospital post discharge

Time frame
Baseline
2

Number of deaths

Number of deaths will be determined by number of patient deaths due to any cause

Time frame
Baseline
3

Change in effective diuresis

Diuresis will be measured from a urine sample and calculated by total diuresis in liters/admission weight in kilograms

Time frame
Baseline, up to 90 Days
4

Change in diuretic dosing

Diuretic dosing will be measured in mg

Time frame
Baseline, up to 90 Days

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Mayo Clinic

Lead sponsor

Source ClinicalTrials.gov
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