A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia
ConditionAnesthesia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMemorial Sloan Kettering Cancer Center
About this trial
The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery. The researchers are particularly interested in the heart function and blood flow changes in people who experience low blood pressure (hypotension) after receiving anesthesia.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adult patients ≥ 18 years of age requiring general anesthesia for surgery
Intubation required for anesthetic management / surgery
Anticipated prep time before incision of 20 minutes
Baseline MAP >70mmHg
Disqualifiers
History of coronary artery disease
History of cardiac disease (e.g., HTN, arrythmias, valvular and structural abnormalities)
History of peripheral artery occlusive disease
Beta-blocker use
Trial population
Adult patients requiring general anesthesia for surgery
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Echocardiography
Diagnostic testEchocardiography and non-invasive blood pressure (NIBP) cuff to measure blood pressure- in anywhere between 2.5 - 5 minute increments before, immediately after anesthesia induction and after intubation for up to 20 minute.
Treatment groups
250 Participants
are divided into 1 treatment groupGroup A: Echocardiography1 intervention
Trial outcomes
Primary outcomes
1
The proportion of patients with post-induction hypotension (PIH)
summarize the distributions of the echocardiography parameter values (pre-load LVEDd(cm), after-load LVEDs(cm), other measures \[e.g., contractility (EF %) and structural abnormalities\]) across each timepoint among patients with and without PIH
Time frame
up to 20-mins after anesthesia induction.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov