A Study of Enterorenal Syndrome Assessed by Gastrointestinal Ultrasound Combined with Renal Artery Resistance Index
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age14-85
SponsorZhangzhou Municipal Hospital
About this trial
In this study, the patients with sepsis caused by abdominal infection were divided into survival group and death group by ultrasound examination of gastrointestinal function, superior mesenteric artery blood flow, and renal artery resistance index. The cross-sectional area of gastric antrum, average time flow rate of superior mesenteric artery, colon diameter, colon peristalsis frequency, and renal artery resistance index of the two groups were compared to determine the progression of entero-renal syndrome as soon as possible. To provide reliable objective basis for clinical decision-making, in order to improve the success rate of rescue.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients diagnosed with intra-abdominal infections
Patients with sepsis or septic shock
Disqualifiers
Patients with open chest or abdominal injury
Patients with advanced tumor
Patients with uremia
Pregnant women
Trial population
In this study, patients who had been admitted into the ICU of our hospital due to sepsis/spetic shock induced by intra-abdominal infections and who had stayed for more than 72 hours.The patients with sepsis caused by abdominal infection were divided into survival group and death group by ultrasound examination of gastrointestinal function, superior mesenteric artery blood flow, and renal artery resistance index. The cross-sectional area of gastric antrum, average time flow rate of superior mesenteric artery, colon diameter, colon peristalsis frequency, and renal artery resistance index of the two groups were compared to determine the progression of entero-renal syndrome as soon as possible.
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
No intervention
Diagnostic testNo intervention
Treatment groups
74 Participants
are divided into 2 treatment groupsGroup A: Survival group1 intervention
Group B: Death group1 intervention
Trial outcomes
Primary outcomes
1
superior mesenteric artery resistance index
With the patient in a supine position, ran the probe along the longitudinal section of the abdominal aorta to reveal the long axis of the superior mesenteric artery, and placed the probe 1.0 to 2.0 cm distal of where the superior mesenteric artery starts. The pulsed wave Doppler was used to show the spectrum of blood flow velocity, where the included angle between the bloodstream and the sound beam ranged from 25° to 45°. The waveform was recorded for three cardiac cycles, and the mean value calculated(Figure 1). The normal value of SMARI was between 0.69\~0.91
Time frame
upon admission into the ICU, and, 24 and 72 hours afterwards2
renal artery resistance index
With the patient in a supine position, ran the probe along the longitudinal section of the abdominal aorta to reveal the long axis of the superior mesenteric artery, and placed the probe 1.0 to 2.0 cm distal of where the superior mesenteric artery starts. The pulsed wave Doppler was used to show the spectrum of blood flow velocity, where the included angle between the bloodstream and the sound beam ranged from 25° to 45°. The waveform was recorded for three cardiac cycles, and the mean value calculated(Figure 1). The normal value of SMARI was between 0.69\~0.91
Time frame
upon admission into the ICU, and, 24 and 72 hours afterwardsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov