This clinical trial tests the feasibility and acceptability of the Strengthening Teen Brain Resilience Using Music (STRUM) intervention to improve radiation induced cognitive decline for adolescents undergoing radiation therapy for cancer treatment. Adolescents treated with radiation therapy for cancer often experience persistent cognitive deficits and reduced brain resilience or the ability to preserve cognitive and emotional functioning despite stressors. Musical instrument training has been shown to enhance memory, academic skills, and emotional well-being in youth. Although guitars are often the most preferred instrument, ukuleles offer greater accessibility due to their simplicity, affordability, and suitability for younger users. The STRUM intervention consists of virtual active music therapy ukulele lessons, which may be a feasible and acceptable way to improve radiation induced cognitive decline for adolescents undergoing radiation therapy for cancer treatment.
Aged 12-17 years at the time of enrollment
Receiving initial radiation therapy (RT) for cancer treatment with curative intent at the Mayo Clinic Arizona
Able to provide assent
Able to read and write in English
Less than three-month prognosis
Past history of RT
Self-reported visual, hearing, or cognitive impairment impeding the ability to complete the STRUM intervention
Prior receipt of ukulele or guitar lessons
Single group
Interview
Other interventionAncillary studies
Music Therapy
Procedure/SurgeryAttend STRUM sessions
Survey Administration
Other interventionAncillary studies
Percentage of eligible participants who consent to participate in this study (feasibility)
Feasibility defined as achieving a ≥ 70% consent rate among eligible participants.
Proportion of Strengthening Teen Brain Resilience Using Music (STRUM) sessions completed (feasibility)
Participants will receive 10 weekly 30-minute virtual ukulele lessons over ten weeks. Basic descriptive statistical analyses will be performed.
Average weekly practice minutes
Assessed by patient self-report. Participants will be encouraged to practice their skills independently for at least 90 minutes per week. Basic descriptive statistical analyses will be performed.
Percentage of participants who complete ≥ 90% of the measures at each timepoint (feasibility)
Basic descriptive statistical analyses will be performed.
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Mayo Clinic
Lead sponsor
National Cancer Institute (NCI)
Collaborator
This trial is not recruiting at the moment. You can still explore other options:
