About this trial
Visual impairment, whether central or peripheral, may influence the plasticity of other sensory modalities, such as taste and smell. Taste-evoked potentials (TEPs) and smell-evoked potentials (SEPs)-methods for analyzing brain activity in response to taste and smell stimuli-allow for the objective assessment of these interactions. This approach has already demonstrated its value in the study of cognitive disorders. This study aims to demonstrate an enhancement of taste and smell capabilities that could compensate for specific visual impairments, particularly in situations involving food choices.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Adult: ≥ 18 years and ≤ 60 years
Individual who has given oral consent
Individual who has been fasting (no food, drink, or tobacco) for at least 1 hour prior to PEG and PEO measurement
No cognitive complaints and normal neurological examination.
Disqualifiers
Individuals who are not enrolled in or eligible for a social security program
Individuals subject to a legal protective measure (guardianship, conservatorship)
Individuals subject to judicial safeguard measures
Adults who are legally incapacitated or unable to give informed consent
Trial design
Parallel
Treatments tested in this trial
Taste and smell evaluation
Other interventionDetermination of taste and smell ability scores using standardized methods (ETOC and Taste Strips)
Recording of evoked potentials (EP)
Other interventionA recording of gustatory evoked potentials (GEP) and olfactory evoked potentials (OEP) in response to stimuli consisting of sucrose solution, vanillin, and a combination of the two.
Treatment groups
Trial outcomes
Primary outcomes
Average latency of PEG (Taste-Evoked Potentials) peaks
Measurement of the mean latency of taste-evoked potential peaks in visually impaired patients versus control subjects following purely gustatory stimulation (sucrose).
Average amplitude of PEG (Taste-Evoked Potentials) peaks
Measurement of the mean amplitude of taste-evoked potential peaks in visually impaired patients versus control subjects following purely gustatory stimulation (sucrose).
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: