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A Study of the Correlation Between Portal Vein Thrombosis and Prognosis of Liver Transplantation

ConditionPortal Vein Thrombosis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorRu-zhou Cai

About this trial

The goal of this observational study is to investigate the correlation between portal vein thrombosis (PVT) and the prognosis of liver transplantation. The main questions it aims to address are:

What is the prevalence of PVT? What are the risk factors associated with PVT? What is the prognostic impact of preoperative PVT on liver transplantation?

Participants are divided into two groups: the PVT group and the non-PVT group. The investigators will comparatively analyze the data of both groups, estimate the prevalence and risk factors of PVT, construct a predictive model for PVT that is applicable in clinical settings, and clarify the prognostic effects of PVT.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Liver transplantation recipients

Aged 18 years or older.

Disqualifiers

Retransplantation

Multi-organ transplantation

Portal vein tumor thrombus

Trial population

Patients who underwent in situ liver transplantation at the Liver Transplantation Center of Beijing Friendship Hospital affiliated with Capital Medical University from 2016-1-1 to 2025-12-31

Trial design

Design model

Cohort

Time perspective

Other

Treatments tested in this trial

  • Observation

    Other intervention

    No intervention were made.

Treatment groups

700 Participants
are divided into 2 treatment groups
Group A: PVT1 intervention
Group B: non-PVT1 intervention

Trial outcomes

Primary outcomes

1

Death

Rate of death from various causes after liver transplant

Time frame
10 years
2

Postoperative portal vein thrombosis

Number of participants with portal vein thrombosis after liver transplant

Time frame
10 years
3

Postoperative portal vein stenosis

Number of participants with portal vein stenosis after liver transplant

Time frame
10 years

Secondary outcomes

1

Postoperative complications

Rate of re-surgery, interventional operation, endoscopy, dialysis, etc.

Time frame
1 year

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Ru-zhou Cai

Lead sponsor

Beijing Friendship Hospital

Sponsor institution

Source ClinicalTrials.gov
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