主要研究目的：
1)探讨笑疗法在造血干细胞移植患者移植心理健康及生存质量中的效果。 次要研究目的：
1. 了解造血干细胞移植患者移植后3个月、6个月、1年内的心理健康变化和生存质量水平； 2. 探讨笑疗法在造血干细胞移植患者预后等结局指标中的应用效果。
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Parallel
laughter therapy intervention
BehavioralIn addition, patients in the intervention group were given laughter therapy intervention from the 1st day of HSCT, with the mnemonic "hihihi (pinyin spelling), hahahaha, eggplant eggplant eggplant, qixi qixi qixi qixi, hahahahahahahahaha," 30 times of the mnemonic as a training session, once a day, from the beginning of the transplantation transfusion +1d to the end of the transplantation transfusion +1d, and then to the end of the transplantation. Patients were discharged from the warehouse, and after discharge, patients were centralized on-line laughter therapy intervention, 1 time/week, repeating 30 times of mnemonics, until 1 year after transplantation.
Overall survival
time between the start of randomization and death from any cause
Progression-free survival
time between the start of randomization and progression of the tumor in any respect or death from any cause
Time to treatment failure
time from start of randomization to withdrawal from the trial, withdrawal may be due to patient refusal, disease progression, death, adverse events
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