The post-hepatotectomy liver failure (PHLF) is still the most worrisome complication of hepatic resection. Surgeons have always been making efforts to preoperatively predict PHLF using kinds of techniques, scoring systems, and variables. The investigators of this study tried to create an individual predictive model based on the variable, resected normal parenchymal volume (RNLV), then assessing the performance and value of the model in clinical practice.
selective hepatectomies;
histologically confirmed as HCC and ICC
complete and accessible data
any history of Associated Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS)
any history of portal vein embolism (PVE)
any history of tumor rupture
emergency surgery
1133 consecutive patients diagnosed with hepatocellular carcinoma (HCC) and intracholangiocarcinoma underwent hepatectomies.
Case-control
Retrospective
the different definitions of PHLF according to 50-50 criteria and ISGLS criteria
Diagnostic testOur study respectively defined the PHLF according to the 50-50 criteria and the ISGLS criteria in literature review.
Probability of PHLF was predicted with our individual model based on RNLV.
In our center, an increase international normalized ratio greater than 1.15 and concomitant hyperbilirubinemia more than 23μmol/L on or after postoperative day 5 would be defined as PHLF, according to the International Study Group of Liver Surgery.
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