A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHoffmann-La Roche

About this trial

The main purpose of the study is to evaluate participant satisfaction after administration of ocrelizumab subcutaneously (SC) after 12 months using the therapy administration satisfaction questionnaire subcutaneous (TASQ-SC).

Eligibility criteria

Qualifiers

Diagnosis of MS

RMS and PPMS participants diagnosed according to the McDonald criteria of 2017 or revised McDonald criteria 2024

First treatment during the course of MS therapy with ocrelizumab SC according to the local prescribing information, regardless of the reason for starting treatment with ocrelizumab

Disqualifiers

Participation in interventional studies investigating DMTs for MS

Prior or simultaneous participation in CONFIDENCE or MoOzaRt (ISRCTN55332718) non interventional study (NIS) at the same study site

Prior treatment with rituximab (MabThera®) or ublituximab (Briumvi®)

Severe psychiatric disability

Trial design

Treatments tested in this trial

  • Ocrelizumab

Treatment groups

842 Participants
are divided into 1 treatment group

Sponsors and collaborators