Accuracy of 3D Electrical Impedance Tomography for Assessing Lung Ventilation
ConditionPulmonary Ventilation
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorShanghai Zhongshan Hospital
About this trial
This prospective observational study will evaluate how accurately three-dimensional electrical impedance tomography (3D-EIT) measures the distribution of air in the lungs during breathing when compared with four-dimensional computed tomography (4D-CT).
3D-EIT is a noninvasive, radiation-free imaging method that measures changes in electrical impedance across the chest and can provide continuous information about regional lung ventilation. In this study, 4D-CT will be used as the reference method because it can provide detailed images of changes in the lungs throughout the breathing cycle.
Approximately 50 adults, including healthy volunteers and hospitalized patients who are able to undergo both examinations, will be enrolled at a single center. EIT and CT data will be collected at the same time during stable breathing. Researchers will compare the two methods to determine how closely their measurements of ventilation in different lung regions agree. The study will also explore whether EIT can detect changes in regional ventilation under different breathing conditions.
The study will not use the research EIT results to make clinical treatment decisions. The findings may support the future use of EIT as a noninvasive, radiation-free method for monitoring regional lung ventilation.
Eligibility criteria
Qualifiers
Age 18 years or older.
Healthy volunteers or patients in the intensive care unit for whom CT imaging is considered necessary based on the treating physician's clinical judgment.
Able to cooperate with or undergo simultaneous 4D-CT and 3D-EIT monitoring.
Able to provide written informed consent personally or through a legally authorized representative, as applicable.
Disqualifiers
Unable to tolerate or having a contraindication to 4D-CT examination, including pregnancy or severe respiratory distress.
Extensive chest skin injury or infection, or any condition preventing placement of the EIT electrode belt.
Body size or chest deformity that may substantially limit the quality of EIT or CT data, including chest circumference outside the compatible range of the EIT device.
Presence of an implanted electronic device that may interfere with EIT signals, such as a cardiac pacemaker.
Trial design
Treatments tested in this trial
- Three-Dimensional Electrical Impedance Tomography
- Dynamic Chest Computed Tomography
Treatment groups
50 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Source ClinicalTrials.gov