About this trial
The main objective of YoungFitT Project is to study the effect and neuro-psycho-biological mechanisms of mind and body interventions, also in the form of virtual reality (VR), on brain health, cognitive and psychological well-being of college students. The investigators have adopted an inter and multidisciplinary and multimodal approach to provide a more integrative perspective using cognitive, psychological, biochemical, and neuroimaging measurements. The investigators hypothesize that all three interventions Mindfulness-Based Stress Reduction (MBSR), Qigong, and High-Intensity Functional Training (HIFT) will produce gains in cognitive functions and psychological well-being at three months compared to baseline. Also, all three interventions will induce changes in the microbiota and brain structure and function. Finally, using a VR environment for these interventions will provide greater adherence and cognitive and psychological well-being benefits than conventional training.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Individuals aged 18-25 years old
Fluency in Catalan or Spanish (I.e., able to understand and speak)
Accept to take part in the study and sign the informed consent according to the Declaration of Helsinki.
Disqualifiers
Severe Neurological or psychiatric history
Alcohol or drug abuse history
Injury that prevents exercise
Claustrophobia
Trial design
Parallel
Treatments tested in this trial
High-Intensity Functional Training (HIFT)
BehavioralThis intervention will include three sessions per week: two group 60-minute zoom online synchronous sessions guided by experts and one individual autonomous session (a repetition of a chosen session of that week). The training protocol will be designed based on Cross-Training workouts, emphasizing high-intensity interval training combined with functional resistance-training movements.
Mindfulness-Based Stress Reduction Program (MBSR)
BehavioralThis intervention follows the official MBSR program designed by Jon Kabat-Zinn with some adaptations, as we did in Bermudo-Gallaguet, et al. (2022). The intervention will occur three days a week, including one 120-minute online synchronous session and two 20-40 min individual practices. The intensity of physical exercise will be adjusted to personal baseline characteristics.
Qigong
BehavioralThis intervention will include three sessions per week: two group 60-minute zoom online synchronous sessions guided by experts and one individual autonomous session (a repetition of a chosen session of that week). The program includes the Baduanjin sequence, considered one of the most ancient and beneficial forms for physical and mental health within the Qigong tradition.
Treatment groups
Trial outcomes
Primary outcomes
Changes in immediate verbal attention
Direct Digit Span, subtest from the Wechsler Adult Intelligence Scale - Third Edition (WAIS-III). Span. Direct score. Range 0-9. Higher scores indicate better performance.
Changes in processing speed
Symbol-Digit Coding subtest from the Wechsler Adult Intelligence Scale - Third Edition (WAIS-III). Direct score. Range 0-133. Higher scores indicate better performance.
Changes in visual attention
Trail Making Test Part A. Seconds to complete the numerical sequence. Direct score. More time indicates worse performance.
Changes in verbal memory
Rey Auditory Verbal Learning Test. Direct score. Range 0-75. Higher scores indicate better performance.
Secondary outcomes
Changes in Physical activity
International Physical Activity Questionnaire (IPAQ). Total physical activity measured in MET-min/week through the International Physical Activity Questionnaire - Short Form. Direct score. Higher scores indicate more physical activity.
Changes in Anthropometric Measurements - Height
Height in meters
Changes in Anthropometric Measurements - Weight
Weight in Kg
Changes in Anthropometric Measurements - Body Mass
Body mass index (BMI)
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Barcelona
Lead sponsor
University Ramon Llull
Collaborator
ICREA Academia
Collaborator
Institut de Neurociències de la Universitat de Barcelona
Collaborator
Institut de Recerca Sant Joan de Déu (CERCA center)
Collaborator
EventLab
Collaborator
INEFC
Collaborator
Nirakara Lab
Collaborator
Adventhealth Research Institute, Neuroscience
Collaborator
University of Murdock
Collaborator