Active Young, Healthy Mind. The YoungFitT Project

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-25
SponsorUniversity of Barcelona

About this trial

The main objective of YoungFitT Project is to study the effect and neuro-psycho-biological mechanisms of mind and body interventions, also in the form of virtual reality (VR), on brain health, cognitive and psychological well-being of college students. The investigators have adopted an inter and multidisciplinary and multimodal approach to provide a more integrative perspective using cognitive, psychological, biochemical, and neuroimaging measurements. The investigators hypothesize that all three interventions Mindfulness-Based Stress Reduction (MBSR), Qigong, and High-Intensity Functional Training (HIFT) will produce gains in cognitive functions and psychological well-being at three months compared to baseline. Also, all three interventions will induce changes in the microbiota and brain structure and function. Finally, using a VR environment for these interventions will provide greater adherence and cognitive and psychological well-being benefits than conventional training.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Individuals aged 18-25 years old

Fluency in Catalan or Spanish (I.e., able to understand and speak)

Accept to take part in the study and sign the informed consent according to the Declaration of Helsinki.

Disqualifiers

Severe Neurological or psychiatric history

Alcohol or drug abuse history

Injury that prevents exercise

Claustrophobia

Trial design

Design model

Parallel

Treatments tested in this trial

  • High-Intensity Functional Training (HIFT)

    Behavioral

    This intervention will include three sessions per week: two group 60-minute zoom online synchronous sessions guided by experts and one individual autonomous session (a repetition of a chosen session of that week). The training protocol will be designed based on Cross-Training workouts, emphasizing high-intensity interval training combined with functional resistance-training movements.

  • Mindfulness-Based Stress Reduction Program (MBSR)

    Behavioral

    This intervention follows the official MBSR program designed by Jon Kabat-Zinn with some adaptations, as we did in Bermudo-Gallaguet, et al. (2022). The intervention will occur three days a week, including one 120-minute online synchronous session and two 20-40 min individual practices. The intensity of physical exercise will be adjusted to personal baseline characteristics.

  • Qigong

    Behavioral

    This intervention will include three sessions per week: two group 60-minute zoom online synchronous sessions guided by experts and one individual autonomous session (a repetition of a chosen session of that week). The program includes the Baduanjin sequence, considered one of the most ancient and beneficial forms for physical and mental health within the Qigong tradition.

Treatment groups

219 Participants
are divided into 3 treatment groups
Group A: High-Intensity Functional Training (HIFT) GroupExperimental treatment 1 intervention
Group B: Mindfulness GroupExperimental treatment 1 intervention
Group C: Qigong GroupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Changes in immediate verbal attention

Direct Digit Span, subtest from the Wechsler Adult Intelligence Scale - Third Edition (WAIS-III). Span. Direct score. Range 0-9. Higher scores indicate better performance.

Time frame
Baseline (2 weeks before) & follow-up (2 weeks after completing interventions)
2

Changes in processing speed

Symbol-Digit Coding subtest from the Wechsler Adult Intelligence Scale - Third Edition (WAIS-III). Direct score. Range 0-133. Higher scores indicate better performance.

Time frame
Baseline (2 weeks before) & follow-up (2 weeks after completing interventions)
3

Changes in visual attention

Trail Making Test Part A. Seconds to complete the numerical sequence. Direct score. More time indicates worse performance.

Time frame
Baseline (2 weeks before) & follow-up (2 weeks after completing interventions)
4

Changes in verbal memory

Rey Auditory Verbal Learning Test. Direct score. Range 0-75. Higher scores indicate better performance.

Time frame
Baseline (2 weeks before) & follow-up (2 weeks after completing interventions)

Secondary outcomes

1

Changes in Physical activity

International Physical Activity Questionnaire (IPAQ). Total physical activity measured in MET-min/week through the International Physical Activity Questionnaire - Short Form. Direct score. Higher scores indicate more physical activity.

Time frame
Baseline (2 weeks before) & follow-up (2 weeks after completing interventions)
2

Changes in Anthropometric Measurements - Height

Height in meters

Time frame
Baseline (2 weeks before) & follow-up (2 weeks after completing interventions)
3

Changes in Anthropometric Measurements - Weight

Weight in Kg

Time frame
Baseline (2 weeks before) & follow-up (2 weeks after completing interventions)
4

Changes in Anthropometric Measurements - Body Mass

Body mass index (BMI)

Time frame
Baseline (2 weeks before) & follow-up (2 weeks after completing interventions)

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Barcelona

Lead sponsor

University Ramon Llull

Collaborator

ICREA Academia

Collaborator

Institut de Neurociències de la Universitat de Barcelona

Collaborator

Institut de Recerca Sant Joan de Déu (CERCA center)

Collaborator

EventLab

Collaborator

INEFC

Collaborator

Nirakara Lab

Collaborator

Adventhealth Research Institute, Neuroscience

Collaborator

University of Murdock

Collaborator