Acute Effects of High-intensity Interval Training With Mindfulness-based Recovery on Executive Function in Children

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age10-12
SponsorPurdue University

About this trial

The goal of this randomized cross-over trial is to learn about the effect of a single bout of 20-min mindfulness-based high-intensity interval training (MF-HIIT), MF-only, and HIIT-only in relative to sitting rest on executive function (EF) in 10-12 years old children. The main question it aims to answer are:

Question 1: Whether a single bout of 20-min MF-HIIT has larger beneficial effect on EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest

Question 2: Whether a single bout of 20-min MF-HIIT has a larger beneficial effect on brain functioning, as measured by the N2 and P3 components of event-related potential (ER) during EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest

Participants will visit the laboratory on 5 separate days (\> 2-day washout between days) in which they have not previously participated in structured physical activities.

Participants will complete the testing and/or receive treatments below:

Day 1:

* Kaufman Brief Intelligence Test (KBIT) to assess intelligence quotient * Treadmill-based exercise test to measure cardiorespiratory fitness (maximum oxygen consumption)

Days 2-5

* Each day, participants will complete each of the four intervention conditions (MF-HIIT, MF-only, HIIT-only, sitting) * Participants' heart rate and self-reported affect and rating of physical exertion will be measured * Participants will complete a modified flanker task and a task-switching task to assess inhibitory control and cognitive flexibility * Participants will wear an EEG cap to measure the N2 and P3 components of the event-related potential during the inhibitory control and cognitive flexibility performance

Researcher will compare the cognitive outcome measures following the MF-HIIT, MF-only, and HIIT-only conditions with the sitting condition to see if MF and HIIT has beneficial effects on children's EF.

Further, researcher will compare the cognitive outcome measures following the MF-HIIT compared with MF-only and HIIT-only conditions to see if combining MF with HIIT has greater beneficial effects on children's EF than MF and HIIT alone.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age between 10-12 years old

Intelligence Quotient ≥ 85

Capable of performing exercise based on pre-participation health screening

No formal diagnosis of cognitive disorders (e.g., attention deficit hyperactivity disorder) and neurological diseases (e.g., epilepsy)

Disqualifiers

Age outside of the range of 10-12 years old

Intelligence Quotient < 85

No capable of performing exercise based on pre-participation health screening

Has formal diagnosis of cognitive disorders (e.g., attention deficit hyperactivity disorder) and neurological diseases (e.g., epilepsy)

Trial design

Design model

Crossover

Treatments tested in this trial

  • MF-HIIT

    Behavioral

    A single bout of 20-min MF-HIIT protocol delivered through a motor-driven treadmill. The protocol will start with a 1.5-min warm-up, then a 16.5-min main exercise (6 x 90s exercise intervals separated by 5 x 90s mindful intervals), and finally a 2-min cool-down.

  • MF-only

    Behavioral

    A single bout of 20-min intervention mindfulness intervention that includes 5 x 90s mindful intervals separated by sitting rest

  • HIIT-only

    Behavioral

    A single bout of 20-min HIIT protocol delivered through a motor-driven treadmill. The protocol will start with a 1.5-min warm-up, then a 16.5-min main exercise (6 x 90s exercise intervals separated by 5 x 90s rest intervals), and finally a 2-min cool-down.

  • Sitting rest

    Behavioral

    Participants will sit in a comfortable chair, placed on the treadmill, while watching a HIIT video without mindfulness instructions for 20 minutes.

Treatment groups

60 Participants
are divided into 4 treatment groups
Group A: A Single Bout Of Mindful High-Intensity Interval Training (Mindful HIIT)Experimental treatment 1 intervention
Group B: A Single Bout Of High-Intensity Interval Training (HIIT)Active comparator 1 intervention
Group C: A Single Bout Of MindfulnessActive comparator 1 intervention
Group D: A Single Bout Of Sitting RestOther 1 intervention

Trial outcomes

Primary outcomes

1

Inhibition speed

Inhibition speed will be assessed by the response time (ms) during a child-friendly flanker task.

Time frame
At the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.
2

Inhibition accuracy

Inhibition accuracy will be assessed by the response accuracy (%) during a child-friendly flanker task.

Time frame
At the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.
3

Shifting speed

The shifting speed will be assessed by the response time (ms) during a child-friendly switching task.

Time frame
At the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.
4

Shifting accuracy

The shifting accuracy will be assessed by the response accuracy (%) during a child-friendly switching task.

Time frame
At the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

Secondary outcomes

1

State Mindfulness Scale for Physical Activity (SMSPA)

A developmentally-appropriate and validated 12-item, 5-point Likert scaled (0-4), instrument to measure self-reported mindfulness state in children aged above 10 years old. This measure will serve as a manipulation check on mindfulness induction during each of the 4 intervention conditions.

Time frame
Immediately after completing the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.
2

Rating of perceived exertion

The 10-point Children's OMNI rating of perceived exertion will be used as a manipulation check on the intensity of prescribed exercise for the school-based programs as well as the laboratory-based acute interventions.

Time frame
Measure at 0 second, 90 seconds, 180 seconds, 270 seconds, 360 seconds, 450 seconds, 540 seconds, 630 seconds, 720 seconds, 810 seconds, 900 seconds, 990 seconds, 1080 seconds and 1200 seconds of the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.
3

Heart Rate

Heart rate will serve as a manipulation check on the intensity of prescribed exercise.

Time frame
Heart rate will be measured at every minute (minutes 0, 1, 2, 3, 4, ...., 18, 19, 20) during the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

Other outcomes

1

Dispositional mindfulness

Child and Adolescent Mindfulness Measure (CAMM) provides a validated and reliable measure of dispositional mindfulness in children using 10 items and 5-point Likert scale (0-4), with a higher total score indicating the participant is more mindful. This measure will be used as the secondary outcome measure to to check the intervention manipulation.

Time frame
At baseline on Day 1 before receiving any intervention

Sponsors and contacts

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Purdue University

Lead sponsor

University of Oregon

Collaborator