About this trial
The goal of this randomized cross-over trial is to learn about the effect of a single bout of 20-min mindfulness-based high-intensity interval training (MF-HIIT), MF-only, and HIIT-only in relative to sitting rest on executive function (EF) in 10-12 years old children. The main question it aims to answer are:
Question 1: Whether a single bout of 20-min MF-HIIT has larger beneficial effect on EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest
Question 2: Whether a single bout of 20-min MF-HIIT has a larger beneficial effect on brain functioning, as measured by the N2 and P3 components of event-related potential (ER) during EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest
Participants will visit the laboratory on 5 separate days (\> 2-day washout between days) in which they have not previously participated in structured physical activities.
Participants will complete the testing and/or receive treatments below:
Day 1:
* Kaufman Brief Intelligence Test (KBIT) to assess intelligence quotient * Treadmill-based exercise test to measure cardiorespiratory fitness (maximum oxygen consumption)
Days 2-5
* Each day, participants will complete each of the four intervention conditions (MF-HIIT, MF-only, HIIT-only, sitting) * Participants' heart rate and self-reported affect and rating of physical exertion will be measured * Participants will complete a modified flanker task and a task-switching task to assess inhibitory control and cognitive flexibility * Participants will wear an EEG cap to measure the N2 and P3 components of the event-related potential during the inhibitory control and cognitive flexibility performance
Researcher will compare the cognitive outcome measures following the MF-HIIT, MF-only, and HIIT-only conditions with the sitting condition to see if MF and HIIT has beneficial effects on children's EF.
Further, researcher will compare the cognitive outcome measures following the MF-HIIT compared with MF-only and HIIT-only conditions to see if combining MF with HIIT has greater beneficial effects on children's EF than MF and HIIT alone.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age between 10-12 years old
Intelligence Quotient ≥ 85
Capable of performing exercise based on pre-participation health screening
No formal diagnosis of cognitive disorders (e.g., attention deficit hyperactivity disorder) and neurological diseases (e.g., epilepsy)
Disqualifiers
Age outside of the range of 10-12 years old
Intelligence Quotient < 85
No capable of performing exercise based on pre-participation health screening
Has formal diagnosis of cognitive disorders (e.g., attention deficit hyperactivity disorder) and neurological diseases (e.g., epilepsy)
Trial design
Crossover
Treatments tested in this trial
MF-HIIT
BehavioralA single bout of 20-min MF-HIIT protocol delivered through a motor-driven treadmill. The protocol will start with a 1.5-min warm-up, then a 16.5-min main exercise (6 x 90s exercise intervals separated by 5 x 90s mindful intervals), and finally a 2-min cool-down.
MF-only
BehavioralA single bout of 20-min intervention mindfulness intervention that includes 5 x 90s mindful intervals separated by sitting rest
HIIT-only
BehavioralA single bout of 20-min HIIT protocol delivered through a motor-driven treadmill. The protocol will start with a 1.5-min warm-up, then a 16.5-min main exercise (6 x 90s exercise intervals separated by 5 x 90s rest intervals), and finally a 2-min cool-down.
Sitting rest
BehavioralParticipants will sit in a comfortable chair, placed on the treadmill, while watching a HIIT video without mindfulness instructions for 20 minutes.
Treatment groups
Trial outcomes
Primary outcomes
Inhibition speed
Inhibition speed will be assessed by the response time (ms) during a child-friendly flanker task.
Inhibition accuracy
Inhibition accuracy will be assessed by the response accuracy (%) during a child-friendly flanker task.
Shifting speed
The shifting speed will be assessed by the response time (ms) during a child-friendly switching task.
Shifting accuracy
The shifting accuracy will be assessed by the response accuracy (%) during a child-friendly switching task.
Secondary outcomes
State Mindfulness Scale for Physical Activity (SMSPA)
A developmentally-appropriate and validated 12-item, 5-point Likert scaled (0-4), instrument to measure self-reported mindfulness state in children aged above 10 years old. This measure will serve as a manipulation check on mindfulness induction during each of the 4 intervention conditions.
Rating of perceived exertion
The 10-point Children's OMNI rating of perceived exertion will be used as a manipulation check on the intensity of prescribed exercise for the school-based programs as well as the laboratory-based acute interventions.
Heart Rate
Heart rate will serve as a manipulation check on the intensity of prescribed exercise.
Other outcomes
Dispositional mindfulness
Child and Adolescent Mindfulness Measure (CAMM) provides a validated and reliable measure of dispositional mindfulness in children using 10 items and 5-point Likert scale (0-4), with a higher total score indicating the participant is more mindful. This measure will be used as the secondary outcome measure to to check the intervention manipulation.
Sponsors and contacts
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Purdue University
Lead sponsor
University of Oregon
Collaborator