Acute Effects of Progressive Muscle Relaxation on Brain Waves

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorKaohsiung Medical University

About this trial

In modern environments, stress is present regardless of age or social role. Stress does not always have negative effects; in fact, it is a necessary response for survival, known as the stress response. This response includes increased heart rate, blood pressure, blood glucose levels, and decreased alpha brainwave activity. These physiological changes are primarily regulated by the sympathetic and parasympathetic branches of the autonomic nervous system, enabling us to cope with environmental threats. However, when the stress response system becomes overwhelmed or imbalanced-whether due to accumulated chronic stress or acute stress-it may result in adverse effects on both physical and mental health.

Relaxation techniques are non-pharmacological methods that promote parasympathetic nervous system activity. The goal is to reduce excessive arousal, alleviate anxiety, slow down thought processes, and relieve stress, thereby achieving relaxation in a natural way. These methods help lower blood pressure, improve circulation, relax muscles, and enhance concentration. Previous studies have demonstrated a correlation between relaxation and attention, suggesting that relaxation can improve attentional efficiency. Moreover, it is well-documented that executive function tends to decline under stress. Relaxation techniques are commonly incorporated into psychological therapies, yet they are more accessible, easier to practice, and can be conveniently performed at home.

Therefore, the aim of this study is to investigate whether PMR can produce immediate relaxation effects as measured by EEG (cortical excitability), heart rate variability, and muscle tone, and whether it can improve performance under psychological stress. The goal is to further explore the potential application of PMR in healthy populations facing acute stress conditions.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Healthy adults

Age: 18 years and above

Body Mass Index (BMI) between 18 and 24

Able to remain in a semi-recumbent position for 2 hours

Disqualifiers

Individuals with communication impairments or difficulty understanding instructions

Color vision deficiency

Open wounds or injuries on the scalp

Currently taking medications that affect cardiovascular or autonomic nervous system regulation

Trial design

Design model

Crossover

Treatments tested in this trial

  • progressive muscle relaxaiton

    Other intervention

    Participants will undergo approximately 30 minutes of Progressive Muscle Relaxation (PMR). Prior to the session, a brief introduction to the basic concepts of PMR will be provided. Participants will be instructed to close their eyes and focus on the sensations in their muscles. Following verbal instructions, they will sequentially contract and relax 14 major muscle groups from top to bottom. For each muscle group, participants will be asked to contract the muscles as strongly as possible for 7 seconds, followed by a 45-second relaxation period. This process will be repeated twice for each muscle group.

  • Rest

    Other intervention

    Rest in a semi-recumbent position with eyes closed for 30 minutes, without any additional intervention.

Treatment groups

32 Participants
are divided into 2 treatment groups
Group A: progressive muscle relaxationExperimental treatment 2 interventions
Group B: restPlacebo comparator 2 interventions

Trial outcomes

Primary outcomes

1

Electroencephalography

Analysis of changes in EEG band power excitability across the frontal, central, and occipital brain regions.

Time frame
20 min in total

Secondary outcomes

1

Muscle tension

Changes in muscle tension

Time frame
15 mins
2

heart rate variability

changes in frequency domain heart rate variability

Time frame
20 mins in total
3

Self-Assessment Manikin

Whether the subjective emotion is calm or excited

Time frame
1min

Other outcomes

Sponsors and contacts

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