Acute Effects of Transcutaneous Electrical Nerve Stimulation at Acupoints on Nociceptive Transmission

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20+
SponsorChina Medical University Hospital

About this trial

The goal of this clinical trial is to learn if transcutaneous electrical nerve stimulation (TENS) applied to acupoints can modulate pain transmission and cortical processing in healthy adult volunteers. The main questions it aims to answer are:

* Does TENS at Zhongzhu (SJ3) and Hegu (LI4) change pain-related evoked potentials (PREPs)? * Does acupoint electrical stimulation alter nociceptive pathways reflected by PREP waveform modulation?

Researchers will compare PREPs recorded before and after TENS at the two acupoints to see if TENS produces measurable effects on cortical nociceptive responses.

Participants will receive low-frequency TENS applied to Zhongzhu (SJ3) and Hegu (LI4), and undergo PREP assessments before and after the intervention to measure cortical responses to standardized noxious stimuli.

Eligibility criteria

Qualifiers

Healthy Adult

20 years or older

The absence of chronic medical conditions

No history of drug allergies

Disqualifiers

History of malignant tumors

History of hand disorders

Has implanted cardiac pacemakers

Pregnancy

Trial design

Treatments tested in this trial

  • transcutaneous electrical nerve stimulation (TENS)
  • EEG machine

Treatment groups

35 Participants
are divided into 1 treatment group