About this trial
The AMPHIBIA study is an observational ambispective and prospective cohort that aim to describe the histologic, immunologic, biological, imaging, genetic and clinical characteristics of the patients hospitalized for an acute myocarditis and to evaluate their association with prognosis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Acute myocarditis confirmed by cardiac magnetic resonance according to Lake Louise modified criteria or by endomyocardial biopsy according to histologic, immunologic and immunohistochemic criteria.
affiliation to the French Health Care System "Sécurité sociale"
Disqualifiers
Severe valvulopathy
Complex congenital cardiopathy
Previous heart transplant
Known significative coronary disease
Trial population
Patients hospitalised at Pitié-Salpêtrière hospital (Paris, France) for an acute myocarditis.
Trial design
Cohort
Other
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Major cardiac events
Defined as a composite of : * All cause death * Resuscitated cardiac arrest * Heart transplant * Longterm mechanical circulatory support * Ventricular arrhythmia after discharge * Hospitalization for heart failure * Hospitalization for myocarditis recurrence
Secondary outcomes
Major cardiac events
Defined as a composite of : * All cause death * Resuscitated cardiac arrest * Heart transplant * Longterm mechanical circulatory support * Ventricular arrhythmia after discharge * Hospitalization for heart failure * Hospitalization for myocarditis recurrence
All cause death
Cardiovascular death
Heart transplant
Number of patients with heart transplant
Sponsors and contacts
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