Adapted Cardiopulmonary Resuscitation Study

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorJohannes Kepler University of Linz

About this trial

The goal of this controlled single centre RCT is to compare frequency rates concerning return of spontaneous circulation (ROSC) in prehospital cardiac arrest. Two different algorithms (control-and interventiongroup) of advanced cardiac life support will be used to treat patients. In patients over 18 years suffering from cardiac arrest. The main question aims to answer if the frequency of ROSC differs between the groups receiving either the new Advanced Life Support (ALS) algorithm, or standard treatment.

Researchers will compare the new algorithm to the standard care algorithm to see if there is a difference .

Participants will be randomized to treatment on scene. The controlgroup will receive ALS standard treatment as performed in local protocols.

The intervention group will receive a modified treatment including:

* thorax compression via mechanical device (LUCAS 3) * head up Cardiopulmonary Resuscitation (cpr) * use of an impendance threshold device (ITD) module * arterial line placement * continuous epinephrin infusion via infusion pump * double sequence defibrillation

Eligibility criteria

Qualifiers

Age> 18 years

time of resuscitation <21 minutes when enrollement starts

Disqualifiers

obvious pregnancy

contraindications for the use of Lucas 3

time of resuscitation >21 minutes and etCO2 <15 mmHg upon arrival of the emergency physician on scene

Exclusion from the emergency physician from study due to futility.

Trial design

Treatments tested in this trial

  • aCPR algorithm
  • ERC ALS 2025

Treatment groups

216 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Johannes Kepler University of Linz

Lead sponsor

Red Cross Upper Austria

Collaborator

Kepler University Hospital

Collaborator