Additive Effects of Alternative Nostril Breathing with Pharmacological Management on Dyspnea and Control Pause in Patients with Bronchial Asthma

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorFoundation University Islamabad

About this trial

Bronchial asthma is a widespread chronic condition charactrized by inflammation and narrowing of airways, leading to repeateted episodes of breathlessness, wheezing and labored breathing.Breathing exercises help to manage hyperventilation often seen in asthmatic patients. To handle respiratory complications asthmatics are advised to practise nasal breathing techniques in conjunction with their prescribed medications.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults: aged (18-45 years)

Gender: Both males and females

Grade1- Grade 4 on Modified MRC dyspnea scale

Asthma severity classes (intermediate, mild persistent and moderate persistent asthma) acc. to NAEPP national asthma education and prevention program guidlin

Disqualifiers

Patients having acute exacerbation of COPD or status asthmaticus

Patients diagnosed with acute infections

Patients unable to follow command/ instructions

Asthma patients with >40 sec control pause duration

Trial design

Design model

Parallel

Treatments tested in this trial

  • Alternative nostril breathing

    Other intervention

    Patients in this group will receive alternative nostril breathing along with pharmacological management. For alternative nostirl breathing patient will be advised to inhale slowly (4sec) and deeply through left nostril.Then hold breath for 2-3 sec. Release right nostril and use right ring finger to close left nostril. Exhale slowly (6sec) and completely through right nostril. Inhale slowly (4sec) and deeply through right nostril. Then hold breath for 2-3sec. Release left nostril and use right thumb to close right nostril. Exhale slowly (6sec) and completely through left nostril. Repeat the cycle.

  • Pharmacological therapy

    Drug

    Participants in this group will only be provided with standard pharmacological management for 4 weeks as prescribed by a pulmonologist. For example: Salbutamol inhaler (Short acting bronchodilator) Saltra inhaler (Selective long acting β2 adrenoceptor agonist) Tiotropium (Anticholinergic) Combivir (Nucleoside analogue - reverse transcriptase inhibitor) etc. Week 01 and week 02: Patients will receive medication prescribed by pulmonologist. Week 03 and week 04: Patients will receive medication prescribed by pulmonologist.

Treatment groups

32 Participants
are divided into 2 treatment groups
Group A: Nostril Breathing along with pharmacological therapy GroupExperimental treatment 2 interventions
Group B: Pharmacological therapy GroupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Dyspnea

Evaluation will be done using Dyspnea-12 questionnaire for dyspnea

Time frame
4 weeks
2

Control pause

Stopwatch will be used to measure control pause.

Time frame
4 weeks
3

Asthma control

Asthma control test (ACT) will be used to evaluate asthma control and peak flow meter for peak expiratory flow rate.

Time frame
4 weeks
4

Peak expiratory flow rate.

Peak flow meter will be used to measure peak expiratory flow rate

Time frame
4 Weeks

Secondary outcomes

Other outcomes

Sponsors and contacts

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