Addressing Racial Disparities in Opioid Overdose Using Peer Recovery Coach Training and mHealth Platform

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-99
SponsorFriends Research Institute, Inc.

About this trial

The study aims to adapt an existing Cultural Structural Humility (CSH) training into a video format for peer recovery coaches (PRCs) and refine an AI-driven texting tool to reinforce the training. After refining these tools using user-centered design, a pilot test will be conducted to assess their impact on the uptake of opioid treatment and social services. The study will also evaluate the feasibility and effectiveness of the intervention to inform future large-scale trials.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

≥18 years of age

fluent in English

self-reported non-prescription opioid use <30 days prior to consent

provision of informed consent

Disqualifiers

inability to comprehend text content written at a 3rd grade reading level

physical or visual disability preventing mobile phone use

Trial design

Design model

Parallel

Treatments tested in this trial

  • PRC supported text + AI driven CSDH-enhanced text

    Behavioral

    In interventional Arm-1, PRC-supported text check-ins to participants (3x/week) will be provided by PRC study staff in addition to automated AI-driven texts. The PRC will personalize text "check-ins" to participants based on: (a) baseline CSDH needs (e.g., food insecurity, legal aid); (b) initial intake visit in primary care or challenges with service entry; and (c) content outlined in the CSH training addressing emerging participant challenges.

  • AI driven CSDH-enhanced text only

    Behavioral

    In interventional Arm-2, participants will receive the AI-driven CSDH-enhanced text messaging only. Participants in this arm will not receive text support from the PRC.

  • Treatment as Usual (TAU)

    Behavioral

    In Arm-3, the control group, individuals randomized to the control arm will receive treatment as usual (i.e., verbal instructions and NYC Dept of Health pamphlets detailing access to OUD and social services). No services will be provided except for social/clinical service referrals given at the end of each REDCap visit.

Treatment groups

180 Participants
are divided into 3 treatment groups
Group A: Intervention Arm-1: PRC supported text+ AI driven CSDH-enhanced textExperimental treatment 1 intervention
Group B: Intervention Arm-2: AI driven CSDH-enhanced text onlyExperimental treatment 1 intervention
Group C: Control Arm 3- Treatment as UsualPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

Estimated Rate of PRC-PWUO Contact

The number of contacts between Peer Recovery Coaches (PRC) and People Who Use Opioids (PWUO), measured through communication logs.

Time frame
3 months
2

Rate of AI-Driven Texting Use Among PWUO

The frequency of AI-driven text interactions initiated by PWUO, captured through software logs.

Time frame
3 months
3

Change in Felt and/or Anticipated Stigma

The change in felt and/or anticipated stigma pre- and post-intervention, measured by a validated stigma assessment questionnaire.

Time frame
3 months
4

Amount of time to Initial Receipt of Buprenorphine (Self-Reported)

The time (in days) to the initial receipt of buprenorphine, as self-reported by participants.

Time frame
3 months

Secondary outcomes

1

The Amount of Participants That Retain in Treatment

The number of participants continuously retained in buprenorphine treatment over a 12-week period, assessed at the 12-week mark.

Time frame
3 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Friends Research Institute, Inc.

Lead sponsor

Nathan Kline Institute for Psychiatric Research

Collaborator

NYU Langone Health

Collaborator