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Adductor Canal Block With or Without Biceps Femoris Short Head Block in Total Knee Arthroplasty

ConditionTotal Knee Arthroplasty
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorCukurova University

About this trial

Total knee arthroplasty is associated with moderate to severe postoperative pain, which may delay mobilization and recovery. Multimodal analgesia including regional anesthesia techniques is widely used to improve outcomes. The adductor canal block (ACB) provides anteromedial knee analgesia but may not adequately cover the posterolateral region.

The biceps femoris short head (BiFeS) block is a novel motor-sparing regional anesthesia technique targeting the posterolateral capsule of the knee. This randomized controlled trial aims to compare the analgesic efficacy and functional outcomes of ACB combined with BiFeS block versus ACB alone in patients undergoing total knee arthroplasty.

The primary outcome is posterior knee pain at postoperative 6 hours. Secondary outcomes include pain scores within 48 hours, opioid consumption, early and late functional recovery, and opioid-related adverse effects.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

ASA I-III

Adult patients undergoing unilateral primary TKA

Planned spinal anesthesia

Written informed consent

Disqualifiers

Coagulopathy

Drug allergy

BMI > 35

Renal/hepatic failure

Trial design

Design model

Parallel

Treatments tested in this trial

  • Adductor Canal Block

    Procedure/Surgery

    Ultrasound-guided adductor canal block performed with injection of local anesthetic into the adductor canal to block the saphenous nerve and provide postoperative analgesia following total knee arthroplasty.

  • Biceps Femoris Short Head Block

    Procedure/Surgery

    Ultrasound-guided biceps femoris short head block performed with injection of local anesthetic between the biceps femoris short head and femur to target the posterolateral innervation of the knee for postoperative analgesia.

  • Sham Biceps Femoris Short Head Block

    Procedure/Surgery

    Sham ultrasound-guided biceps femoris short head block performed with injection of normal saline at the same anatomical location to maintain blinding without providing active analgesia.

Treatment groups

132 Participants
are divided into 2 treatment groups
Group A: ACB + BiFeSExperimental treatment 2 interventions
Group B: ACB + sham BiFeSActive comparator 2 interventions

Trial outcomes

Primary outcomes

1

Posterior Knee Pain Intensity

Posterior knee pain assessed using the Numeric Rating Scale (NRS, 0-10), where 0 indicates no pain and 10 indicates worst imaginable pain.

Time frame
6 hours postoperatively

Secondary outcomes

1

Postoperative Pain Intensity

Pain intensity at rest and during movement assessed using the Numeric Rating Scale (NRS, 0-10).

Time frame
30 minutes, 1, 6, 12, 24, and 48 hours postoperatively
2

Total Opioid Consumption

Total opioid consumption measured from patient-controlled analgesia (PCA) device and additional opioid requirements, expressed in milligrams of morphine equivalent.

Time frame
0-48 hours postoperatively
3

Rescue Analgesic Use

Requirement for additional analgesic medications (e.g., meperidine, paracetamol, ibuprofen) recorded as yes/no and total doses administered.

Time frame
0-48 hours postoperatively
4

Functional Recovery

Functional recovery assessed by range of motion (ROM), quadriceps muscle strength, time to first ambulation, ability to walk 10 meters without assistance, and performance on the 5-times sit-to-stand test.

Time frame
24 hours, 48 hours, and 6 weeks postoperatively

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cukurova University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: