Adipose Inflammation and Diabetes (FAB)
ConditionObese
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorGöteborg University
About this trial
The study investigates whether the addition of resolution molecules can inhibit inflammation and insulin resistance in human tissue taken from obese individuals, and whether the results of these studies correlate with patient-specific resolution phenotypes.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
BMI 30-40 kg/m2
Ptos (i.e. excess skin) > 3 cm
Patient underwent gastric bypass surgery >2 years ago
Patient has had a stable weight ≥6 months at the time of operation
Disqualifiers
Patients who do not understand spoken and written Swedish
American Society of Anesthesiologists (ASA) classification ≥ 3
Neurological, orthopedic or rheumatologic injury or illness affecting physical ability
Preoperatively known hernia requiring surgical operation
Trial population
The patients participating in this study must have undergone a gastric bypass surgery \>2 years ago, and currently have excess skin of \> 3 cm, thus requiring an abdominoplasty surgery. We only include patients that are obese (BMI 30-40 kg/m2). Patients interested in participating in the study donate the skin and adipose tissue that is discarded during surgery. In addition, they donate blood samples prior to surgery.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
18 Participants
are grouped into 1 trial groupGroup A: Study patients
Trial outcomes
Primary outcomes
1
Inflammatory status
The inflammatory status will be studied in obese patients.
Time frame
2025Sponsors and contacts
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Source ClinicalTrials.gov