Advances in Neuropsychological Diagnostics
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20-100
SponsorIstituto Auxologico Italiano
About this trial
This project is aimed at advancing neuropsychological diagnostics, enriching and modernizing the panorama of both clinical and forensic psychometric testing. The rapid socio-demographic changes, the developments of neuropsychological semiotics and nosography, as well as the growing applicative specialization of neuropsychological assessment make it necessary to introduce further tools to satisfy the diagnostic requests in clinical contexts and more recently in the forensic field (i.e., tests to be administered remotely; bedside screeners; domain-specific in-depth tests; tools for assessing testamentary capacity).
Specifically, the present study aims to: a) develop, calibrate and evaluate the psychometric properties of I and II level clinical and/or forensic neuropsychological tests evaluating instrumental and non-instrumental functions in a sample of neurologically healthy individuals representative of the Italian population ; b) evaluate the cross-sectional and longitudinal clinical usability of the aforementioned tests in clinical samples (patients with neurological and neuropsychiatric pathologies of different etiology).
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Clinical populations: clinical diagnosis of either neurological (e.g., vascular and degenerative aetiologies) or psychiatric disorders.
Healthy controls: not applicable
Disqualifiers
Clinical diagnosis not of interest;
Severe general medical conditions;
Uncorrected vision/hearing deficits.
Presence of brain disorders;
Trial population
Individuals with brain disorders and normotypical.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Neuropsychological instruments
BehavioralCognitive and behavioral tests and questionnaires
Treatment groups
300 Participants
are divided into 2 treatment groupsGroup A: Patients1 intervention
Group B: Healthy controls1 intervention
Trial outcomes
Primary outcomes
1
Change from baseline in Brief Assessment of Social Skills-Dementia (BASS-D)
A screening test of social cognition in neurodegeneration
Time frame
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders2
Change from baseline in Picture Interpretation Test (PIT)
A test of executive functions
Time frame
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders3
Change from baseline in Verbal Reasoning Test (VRT-A) - Absurdity sub-test
A test of verbal reasoning
Time frame
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders4
Change from baseline in Brief Executive Language Screen (BELS)
A language test
Time frame
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disordersSponsors and contacts
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Source ClinicalTrials.gov