Health TrialsbyHealthPanel

Advancing Suicide Intervention Strategies for Teens During High Risk Periods

ConditionsSuicide AttemptsSuicidal IdeationSuicide and Self-harmSuicide Threat
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age11-17
SponsorSeattle Children's Hospital

About this trial

To inform the effective management of adolescent suicide risk by evaluating promising treatments and developing the evidence-base for interventions that are well suited for widespread adoption, sustained quality, and impact.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Provision of signed and dated informed consent form

Youth, aged 11-17

Endorse suicidal ideation and/or behavior

Admitted to acute care (emergency, inpatient medical or inpatient psychiatric) due to suicidality

Disqualifiers

Presence of psychosis, intellectual disability, autism spectrum disorder, eating disorder with unstable vitals

Limited English proficiency that would interfere with the ability to complete study assessments

Trial design

Design model

Parallel

Treatments tested in this trial

  • Safety Planning Intervention+ (SPI+)

    Behavioral

    SPI is focused on how the risk of suicidal crisis waxes and wanes over time. At times of heightened risk, a pre-specified and individualized plan targets the internal warning signs that become the cue to use the safety plan. SPI+ strategies focus on patient's narrative of the suicidal crisis and identifying solutions that are antithetical to progressing in a suicidal crisis. The brief structured intervention is conducted in six key steps. Youth in this condition will be offered weekly follow-up, with a minimum of 4 sessions and a maximum of 8 sessions. The goal is to create a crisis response plan to reduce risk when suicidal crises emerge. With adolescents, SPI+ consists of an individual session to elicit crisis narrative and motivation to utilize the safety plan through psychoeducation and follows six steps to achieve the adolescent's goals and return to safety when suicidal urges are high.

  • Collaborative Assessment and Management of Suicidality (CAMS)

    Behavioral

    CAMS strategies focus on collaborative deconstruction and treatment of the patient-defined drivers- the problems that make suicide compelling to the patient- and utilizes these problem-focused treatment sessions to treat the drivers as directly related to wish to die. Participants will be assigned to CAMS for a minimum of 4 sessions and maximum of eight sessions. This time frame, based on initial data from our pilot work with adolescents and emerging adults (18-25), suggests that a subset of participants resolve their STB in six to eight sessions. CAMS is a clinical intervention designed to modify how clinicians engage, assess and plan treatment with suicidal patients.

  • Treatment As Usual

    Behavioral

    This assigned condition tracks the care received in typical circumstances.

Treatment groups

306 Participants
are divided into 3 treatment groups
Group A: Treatment As Usual (TAU)Active comparator 1 intervention
Group B: Safety Planning Intervention+ (SPI+)Active comparator 1 intervention
Group C: Collaborative Assessment and Management of Suicidality (CAMS)Active comparator 1 intervention

Trial outcomes

Primary outcomes

1

Suicidal events

Change the rate of suicidal events as measured by death by suicide, attempted suicide, preparatory acts toward imminent suicidal behavior, or suicidal ideation resulting in a change in treatment plan or emergency evaluation as measured by the C-SSRS.

Time frame
Suicidal events at 12 months

Secondary outcomes

1

Suicide attempts

Self injurious behavior with intent to die as measured by the C-SSRS

Time frame
Suicide attempts at 12 months
2

Suicidal Ideation

Severity of suicidal ideation as measured by the total score on the Suicidal Ideation Questionnaire Junior (SIQ-Jr. This 15 item measure is rated on a Likert scale, with scores ranging from 0 to 90, with higher scores reflecting worse outcomes and more severe ideation.

Time frame
Change in score from baseline to 12 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Seattle Children's Hospital

Lead sponsor

Nationwide Children's Hospital

Collaborator

Source ClinicalTrials.gov
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