AI-Based Medical Data Analysis for Differentiating Inflammatory vs Degenerative Joint Diseases in Elderly Patients

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age60+
SponsorAssiut University

About this trial

This study aims to evaluate the diagnostic accuracy of AI-assisted imaging analysis in differentiating between inflammatory and degenerative joint diseases in elderly patients. The performance of AI-based analysis will be compared with radiologists' assessments to determine its reliability in clinical practice. In addition, the study will explore imaging features most predictive of each disease type using advanced machine learning techniques. Finally, the feasibility of implementing AI tools in the routine management of geriatric musculoskeletal disorders will be assessed.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age ≥ 60 years

Clinical suspicion or confirmed diagnosis of inflammatory joint disease (e.g., rheumatoid arthritis, psoriatic arthritis) or degenerative joint disease (e.g., osteoarthritis)

Availability of relevant musculoskeletal imaging (X-rays, MRI, or ultrasound) suitable for AI-based analysis

Ability to provide informed consent or have a legal representative consent on behalf of the

Disqualifiers

History of recent joint trauma (within the last 6 months) or previous joint surgery affecting the studied sites

Presence of bone or joint malignancy (primary or metastatic)

Diagnosis of overlapping rheumatologic syndromes or mixed pathology (e.g., RA with concurrent gout, or OA with inflammatory overlap)

Inadequate imaging quality or absence of required imaging modalities

Trial population

Elderly patients (≥60 years) presenting to Assiut University Hospitals with clinical suspicion or diagnosis of musculoskeletal disorders, specifically inflammatory joint diseases (such as rheumatoid arthritis) or degenerative joint diseases (such as osteoarthritis), and who have relevant imaging studies (X-ray, MRI, or ultrasound) available for analysis.

Trial design

Design model

Case-only

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Diagnostic accuracy of AI system

Sensitivity, specificity, and AUC of AI algorithm for differentiating inflammatory from degenerative joint diseases, using imaging data, compared to expert rheumatologist diagnosis

Time frame
Within 12 months from baseline assessment.

Secondary outcomes

Other outcomes

Sponsors and contacts

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