About this trial
The study investigates the effects of alcohol consumption on social and individual behaviors using a within-subject design. Participants, aged 21-30, will attend two laboratory sessions approximately one week apart, participating as part of a dyad (pair). During one session, they will consume an alcoholic beverage, while in the other, they will receive a control beverage, with the order of conditions randomized. This design facilitates direct within-participant comparisons of behaviors and neural activity in intoxicated versus sober states.
To achieve these aims, the study employs EEG technology to explore intra-brain and inter-brain dynamics during social interactions. Additionally, validated self-report questionnaires will capture data on mood, social bonding, and other psychological variables. The findings are expected to enhance understanding of alcohol's role in social reward processes and contribute to developing evidence-based prevention and intervention strategies for alcohol use disorder.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Between the ages of 21 and 30
Regularly consumes alcohol
Disqualifiers
History of adverse reaction to the amount of beverage employed in the study
Have a history of major problems associated with alcohol
Take medications that could adversely interact with alcohol
Have medical conditions that contraindicate alcohol administration
Trial design
Single group
Treatments tested in this trial
Alcohol beverage
DrugThis intervention involves the administration of an alcohol beverage (vodka mixed with juice or soda) in a controlled laboratory setting, targeting a blood alcohol concentration (BAC) of 0.08%. The alcohol is consumed over a 36-minute period in three equal parts.
Control - non alcoholic beverage
Other interventionThis intervention involves the administration of a non-alcoholic control beverage in a controlled laboratory setting. The beverage is matched in volume and palatability to the alcohol condition but co
Treatment groups
Trial outcomes
Primary outcomes
Inter-brain entrainment
Synchronization metrics (e.g., inter-subject PLV, inter-subject correlation) between paired participants, assessed separately in sober and intoxicated conditions
Intra-brain entrainment
The comparison of EEG signal synchronization within the same participant across the alcohol and non-alcohol conditions, reflecting intra-brain activity changes due to alcohol consumption during the hyperscanning task.
Event-Related Potentials (ERP)
Feedback-Related Negativity (FRN), measured both for the operating ("player") and observing ("observer") participant, with comparisons across sobriety conditions
Ambulatory Drinking
Drinking behavior assessed outside the laboratory using ambulatory assessment
Sponsors and contacts
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