Allograft vs. Autograft Nonunion
ConditionNonunion Fracture
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorWake Forest University Health Sciences
About this trial
The purpose of this research study is to find out if patients treated for nonunion fracture with autograft or allograft return to activity faster.
Eligibility criteria
Qualifiers
Patients 18 years or older
Long bone (tibia, femur, and humerus) nonunion appropriate for either study treatment: to be treated with bone graft harvested from a remote site or using reamer harvester (RIA)
Nonunion surgery to be performed at least five months after initial fracture fixation
Prior operative fixation of fracture
Disqualifiers
Patient that speaks neither English nor Spanish
Patients whose treatment plan includes local autograft only (available callus from the nonunion site or no planned bone graft)
Known active infection (defined as any clinical signs or symptoms of active infection, such as fevers, wound redness, warmth, swelling, induration or drainage, and abnormal while blood cell count, erythrocyte sedimentation rate, or C-reactive protein) being treated with antibiotics
Body mass index greater than 50
Trial design
Treatments tested in this trial
- Autograft
- Allograft
Treatment groups
156 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov