This pilot study is testing a short brain training program called neurofeedback in adults with alcohol use disorder. Participants will complete three sessions over about one week. The goal is to learn if this approach is easy to complete, well tolerated, and acceptable to participants. We will also explore whether it is associated with changes in alcohol cravings and drinking.
Adults ages 18-65
Meets DSM-5 criteria for current Alcohol Use Disorder
Willing and able to provide informed consent
Alcohol consumption within the past 30 days
History of epilepsy or seizure disorder (excluding uncomplicated alcohol withdrawal seizures)
Current psychosis, mania, or acute suicidality, or any psychiatric condition that would impair the ability to provide informed consent or safely participate
Acute alcohol intoxication at the time of study visits, as determined by -breathalyzer
Pregnancy or breastfeeding
Single group
EEG Neurofeedback
DeviceParticipants will receive a brief course of EEG-based neurofeedback consisting of three sessions over approximately one week. During each session, scalp electrodes are placed to record brain activity using electroencephalography (EEG). Real-time feedback is provided to guide participants in modulating their brain activity. The neurofeedback protocol targets downregulation of alpha-band activity (8-12 Hz). Training is delivered using a standardized protocol with real-time visual and/or auditory feedback. Each session lasts approximately 20 minutes, with additional time for setup and brief assessments.
Participant retention rate over 1 week
Proportion of participants who complete all study visits
Proportion of participants experiencing adverse events during neurofeedback sessions over 1 week
Number and severity of adverse events
Proportion of scheduled neurofeedback sessions completed over 1 week
Proportion of scheduled neurofeedback sessions completed
Change in alcohol craving (Penn Alcohol Craving Scale [PACS] total score) from baseline to Visit 3 (~1 week)
Alcohol craving will be assessed using the Penn Alcohol Craving Scale (PACS). PACS total scores range from 0 to 30, with higher scores indicating greater alcohol craving. Change in PACS total score from baseline to Visit 3 (\~1 week) will be analyzed.
Change in alcohol consumption measured by Timeline Follow-Back (TLFB) from baseline (Visit 1) to post-intervention (Visit 3, ~1 week)
Alcohol consumption will be assessed using the Timeline Follow-Back (TLFB) method. Change in number of standard drinks over the assessment period from baseline to the final visit will be analyzed.
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