An Exploratory Study of ctDNA-MRD in Predicting the Efficacy of Esophageal Squamous Cell Carcinoma

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorGuangzhou Institute of Respiratory Disease

About this trial

The purpose of this study is to observe and evaluate the correlation between ctDNA-MRD and the therapeutic effect and prognosis of stage II-IVA operable esophageal squamous cell carcinoma.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with stage II-IVA Esophageal squamous cell carcinoma confirmed by clinical pathological staging;

≥18 years;

Eastern Cooperative Oncology Group performance status score (ECOG PS) is 0 ~ 1 points;

Expected survival time ≥ 6 months;

Disqualifiers

Patients with other malignant tumors;

Patient had undergone surgery before admission;

Pregnant or lactating women;

Patients with other serious diseases;

Trial population

Esophageal squamous cell carcinoma patients who were initially diagnosed as stage II-IVA (TNM V8) and planned to undergo radical surgery

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Progression-free survival

Evaluation of progression-free survival rate of esophageal squamous cell carcinoma patients with different MRD status during perioperative period

Time frame
up to 2 year

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: