An Observational Prospective Study of Anesthetic Sensitivity Assessed by Alpha Band Power and Its Association With Emergence Time From Sevoflurane General Anesthesia in Young Adults.

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age35-50
SponsorUniversity of Chile

About this trial

The goal of this observational study is to determine the relationship between brain activity patterns and recovery time in adult patients (ages 35-50, ASA I-II) undergoing elective general anesthesia.

The main question it aims to answer is:

\- Does a lower magnitude of intraoperative alpha wave power correlate with a longer time for patients to emerge from general anesthesia?

Participants will:

* Undergo a standardized general anesthesia (GA) protocol for elective surgery. * Have their EEG activity recorded using a standard clinical BIS™ anesthetic depth monitor during the procedure. * Have their time to awakening precisely measured after the cessation of anesthetic gases.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Elective surgery under general anesthesia

Age 35-50 years

ASA physical status I-II

Disqualifiers

Neurological or psychiatric disorders

Use of psychotropic drugs or opioids

Altered consciousness

BMI > 35 kg/m²

Trial population

Young adult patients undergoing an elective surgery at the Hospital Clínico, University of Chile, Santiago, Chile.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Intraoperative EEG Recording

    Procedure/Surgery

    Patients will be monitored with a frontal EEG during general anesthesia using the BIS Monitor to calculate alpha power

Treatment groups

70 Participants
are divided into 1 treatment group
Group A: Young adults1 intervention

Trial outcomes

Primary outcomes

1

Anesthesia emergence time

Minutes from the end of the sevoflurane administration until eye opening to verbal stimulus

Time frame
60 minutes

Secondary outcomes

1

Relative alpha power

Relative alpha power from the frontal EEG under general anesthesia

Time frame
60 minutes
2

Absolute alpha power

Absolute alpha power from frontal EEG under general anesthesia

Time frame
60 minutes
3

Extubation time

Time from the end of administration of sevoflurane until extubation

Time frame
60 minutes
4

Fentanyl requirements

Total dose of fentanyl (mcg) requirement during general anesthesia

Time frame
1 day

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Chile

Lead sponsor

Center for Advanced Clinical Research (CICA ) - University of Chile

Collaborator

This trial is not recruiting at the moment. You can still explore other options: