Analgesic Effects of Retro-superior Costotransverse Ligament Space Block for Video-assisted Thoracoscopic Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorNanjing First Hospital, Nanjing Medical University

About this trial

The aim of this clinical trial is to investigate the effects of postoperative analgesia during retro-SCTLB(retro superior costotransverse ligament space block) and TPVB(thoracic paravertebral block) in patients undergoing thoracoscopic radical resection of lung cancer。By comparing the dosage of opioid drugs after surgery, the impact of retro-SCTLB and TPVB on the postoperative analgesic effect was evaluated.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients scheduled for thoracoscopic radical lung cancer surgery under general anesthesia;

aged 18-80 years;

BMI 18-30 kg/m²;

ASA classification I-III;

Disqualifiers

Allergy to the study drug or local anesthetic;

History of opioid abuse;

Pre-existing skin infection at the puncture site of ITPN or TPVB;

Peripheral infectious neuropathy;

Trial design

Design model

Parallel

Treatments tested in this trial

  • Ultrasound-guided retro-SCTLB

    Procedure/Surgery

    Patients undergoing thoracoscopic radical resection of lung cancer were selected for the study. Before the surgery, the retro-SCTLB was performed under ultrasound guidance。

  • Ultrasound-guided TPVB

    Procedure/Surgery

    Patients undergoing thoracoscopic radical resection of lung cancer were selected for the study. Before the surgery, the TPVB was performed under ultrasound guidance.

Treatment groups

130 Participants
are divided into 2 treatment groups
Group A: retro-SCTLB groupExperimental treatment 1 intervention
Group B: TPVB groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Postoperative sufentanil dosage

Cumulative sufentanil dosage 24 hour postoperatively

Time frame
24 hour postoperatively

Secondary outcomes

1

NRS(Numeric Rating Scales) score

Postoperative 1, 3, 6, 12, 24 and 48 hour NRS (Numeric Rating Scales) score during the resting and active . Numerical Rating Scale (NRS): This scale is composed of 11 numbers from 0 to 10, with higher numbers increasing the severity of pain.

Time frame
Postoperative 1, 3, 6, 12, 24, 48 hour
2

Opioid dosage

opioid consumption dosage during the operation

Time frame
From the start of the anesthesia until the end of the surgery
3

Adverse reaction

This includes dizziness, nausea, vomiting, etc

Time frame
24, 48 hour postoperatively
4

Time of first ambulation after surgery

The early time of the first postoperative ambulation indicates that the nerves blocks has a good effect.

Time frame
Up to 48 hours postoperative

Other outcomes

Sponsors and contacts

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