Analysis of Biomarkers From Patients With Chorioretinal Diseases
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20-80
SponsorKyungpook National University Hospital
About this trial
This study was conducted to investigate the levels of ocular biomarkers from the patients with chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
age over 20 years
patients requiring ophthalmologic treatments for different degrees of decreasing of visual acuity.
patients with chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration.
control patients asking cataract surgery or vitrectomy for posterior segment nonproliferative disorders.
Disqualifiers
under the age of 20 years
patients that received any anti-vascular endothelial growth factor agent for proliferative disease before taking sample of aqueous humor
patients that did not signed the informed consent of the trial
patients with intraocular inflammations or infections that requiring any pharmaceutical agent
Trial population
A total of 100 patients will be included. 50 patients with chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration. and 50 control patients scheduled for pars plana vitrectomy for nondiabetic retinal disease or phacoemulsification.
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
Chorioretinal diseases
Drugchorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration
Treatment groups
100 Participants
are divided into 2 treatment groupsGroup A: Chorioretinal diseases1 intervention
Group B: Control0 interventions
Trial outcomes
Primary outcomes
1
Biomarkers in ocular fluids
To establish if certain type of chorioretinal diseases group are associated to different concentrations of gene or protein concentration.
Time frame
one monthSponsors and contacts
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Source ClinicalTrials.gov