Analysis of Exhaled Breath From Patients With Lung-/Airway Diseases (BigExBrESs)
ConditionLung-/Airway Diseases
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Zurich
About this trial
Ananlyis of exhaled breath of patients with lung-/airway diseases to identify and distinguish respiratory diseases, and improve the disease manangament.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Signed informed consent
Age ≥ 18 years at study entry
Disqualifiers
Physical or intellectual impairment precluding informed consent or protocol adherence
Known pregnancy
Trial population
General population
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
No intervention
Other interventionno intervention
Treatment groups
5,000 Participants
are divided into 2 treatment groupsGroup A: Lung-/Airway diseases1 intervention
Group B: Controls1 intervention
Trial outcomes
Primary outcomes
1
Molecular breath pattern
Comparison of molecular weights of breath features from patients with different respiratory diseases
Time frame
at baselineSecondary outcomes
1
Change in molecular breath pattern
Change in the molecular breath pattern during the course of the disease (untargeted approach)
Time frame
over one year2
Symptoms
Correlation/Association of molecular weights of specific breath features with symptoms (e.g. dyspnea)
Time frame
at baseline3
Inflammatory markers
Correlation/Association of molecular weights of specific breath features with inflammatory markers (e.g. eosinophils)
Time frame
at baseline4
Controls
Differentiation of molecular breath pattern (m/z ratios of molecules in exhaled breath) between diseased patients and participants without respiratory disease (untargeted approach)
Time frame
at baselineSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Zurich
Lead sponsor
Deep Breath Intelligence (DBI)
Collaborator
Source ClinicalTrials.gov