Analysis of Facial Expressions for Pain Recognition in Fibromyalgia: Using Artificial Intelligence and Biomarkers

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorFaculdade de Ciências Médicas de Minas Gerais

About this trial

Fibromyalgia (FM) is a chronic musculoskeletal pain syndrome with characteristics of generalized body pain, low pain threshold, tenderness and stiffness in muscles, tendons and joints. The assessment of pain in this condition is a challenge due to its subjective nature. A promising approach to assessing pain intensity is facial expression analysis, which can serve as an objective indicator. In addition, research seeks to identify molecular molecular markers to quantify pain. However, the lack of a standardized system has made it difficult to identify reliable markers. In summary, the search for objective methods of assessing pain in fibromyalgia is essential in order to develop more effective more effective treatments. Facial expression analysis and the investigation of molecular markers are promising ways of quantifying pain intensity more accurately and intensity of pain more accurately and reliably in fibromyalgia.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

The inclusion criteria are patients with no diagnosed cognitive deficit and who are willing to take part in the study.

Disqualifiers

Exclusion criteria are patients who use medication that can affect anxiety or depression or inability to understand the instructions.

Trial population

The study will be carried out with adult patients aged between 18 and 65 diagnosed with fibromyalgia at the outpatient clinic of the Faculdade Ciências Médicas de Minas Gerais and Clínica Ampla de Reumatologia in Belo Horizonte. The inclusion criteria were patients with no diagnosed cognitive deficit and who were willing to take part in the study. The exclusion criteria are patients who use medication that can affect anxiety or depression or who are unable to understand the instructions. Thus, once the patients agree to participate, they will be asked to sign the Informed Consent Form (ICF), which will provide detailed information about the nature of the study, the criteria for participation, the possible risks and benefits involved.

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

122 Participants
are grouped into 2 trial groups
Group A: Patients diagnosed with fibromyalgia
Group B: Patients without a diagnosis of fibromyalgia

Trial outcomes

Primary outcomes

1

Use the artificial intelligence tool to analyze the facial expression of patients with fibromyalgia in order to recognize pain.

Use the artificial intelligence tool to analyze the facial expression of patients with fibromyalgia in order to recognize pain. 61 patients with fibromyalgia will be compared with 61 patients without fibromyalgia.

Time frame
The estimated time for the anamnesis is one hour, during which time biological samples will be taken and each patient's facial expressions will be recorded on camera.

Secondary outcomes

1

Biochemical analysis of biomarkers in the detection of pain in fibromyalgia.

122 samples containing 1ml of saliva will be collected in order to check for changes in oxidative stress and nociceptive markers (by spectrophotometry and ELISA).

Time frame
Estimated collection and analysis time: 5 hours of durability

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Faculdade de Ciências Médicas de Minas Gerais

Lead sponsor

Fundação de Amparo à Pesquisa do estado de Minas Gerais

Collaborator

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Collaborator