Analysis of Factors Associated With The Occurrence of Amniotic Fluid Entry in Patients Undergoing Caesarean Section

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age20-50
SponsorSecond Hospital of Shanxi Medical University

About this trial

To compare serum STN (Neuraminic acid-N-acetylgalactose)antigen concentrations in patients undergoing cesarean section and to study the factors associated with amniotic fluid entry.Compare the serum complement C4 concentration in patients in the amniotic fluid admission group with those in the non-admission group to study whether amniotic fluid admission triggers the body's immune response.To record the patients' blood pressure, heart rate, blood oxygen, and the occurrence of related symptoms and adverse reactions at the time of admission, at the time of blood collection, at the time of discharge from the room, and at the time of the occurrence of haemodynamic changes.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Approved consent and informed consent of the patient by the Ethics Committee of the Second Hospital of Shanxi Medical University;

ASA classification of I-III;

Age 20-50 years old;

No previous history of psychiatric diseases or psychotropic drugs;

Disqualifiers

Suffer from diseases of the cardiorespiratory system;

Those with communication difficulties who were unable to complete the screening questionnaire;

Trial population

Patients in the Second Hospital of Shanxi Medical University from May 2025 to November 2025

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

  • Enzyme-linked immunosorbent assay

    Diagnostic test

    Serum STN and C4 levels were detected

Treatment groups

120 Participants
are divided into 2 treatment groups
Group A: Amniotic fluid into the blood group1 intervention
Group B: the control group1 intervention

Trial outcomes

Primary outcomes

1

STN

Serum STN levels

Time frame
24 hours
2

C4

Serum C4 levels

Time frame
24 hours

Secondary outcomes

Other outcomes

Sponsors and contacts

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