Achalasia is an uncommon disorder that results from the degeneration of ganglion cells of the myenteric plexus in the lower esophageal wall. Peroral endoscopic myotomy (POEM) is a minimally invasive procedure capable of overcoming limitations of achalasia treatments. This study aimed to: 1) identify the prevalence of reflux esophagitis and asymptomatic GERD in patients who underwent POEM, and 2) evaluate patient and intraprocedural variables associated with post-POEM GERD.
Males and females who are 18 years of age and older and are willing to sign an Informed Consent Form (ICF)
Achalasia patients who underwent POEM
Lack of written consent for participation in the study
Conditions which are contraindication to Esophagogastroscopy and High-resolution Esophageal Manometry
All patients treated at a single center who had a complete GERD evaluation after POEM will be included in the study. Demographics, preoperative and follow-up data, results of functional studies and procedural data will be collected and analyzed.
Cohort
Prospective
Patients who underwent POEM
Other interventionchalasia patients were recruited from a single center. The pre- and postoperative assessments included Eckardt scores, GerdQ questionnaire, high-resolution esophageal manometry, esophagogastroscopy and pH monitoring.
The prevalence of gastroesophageal reflux after peroral endoscopic myotomy (POEM)
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