Analysis of Trunk and Center of Mass Control Development During Gait in Children With Cerebral Palsy (VERTEBRAL)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-18
SponsorUnion de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est

About this trial

During the acquisition of posturokinetic abilities such as walking, postural control of the trunk is of paramount importance. Indeed, its development is strongly linked to the overall motor function of children. In cerebral palsy (CP), a term that refers to a set of motor disorders following a perinatal lesion, deficits in axial control are present from early childhood. These deficits are strongly correlated with the functional deficits observed in this population. In particular, during walking, deviations of the trunk (amplitudes, accelerations) are observed in the three planes of space. While recent literature increasingly questions the impact of trunk control deficit on the walking of children with CP, elements are still missing for a holistic understanding of the interaction between locomotor and postural disorders in children with CP. In particular, no study has focused on the deviations of trunk control and the center of mass (which is a global indicator of balance strategies) during the development and maturation of walking in children with CP. Therefore, the primary objective of this cross-sectional observational study will be to characterize the development of trunk control and center of mass during walking in children with CP.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Children (< 18 years) with cerebral palsy

GMFCS I to III

Independent walking with or without technical walking aids (walker, crutches, etc.)

Able to understand the instructions of various clinical assessments and functional explorations

Disqualifiers

Neuro-orthopaedic surgery of the lower limbs or trunk within the last 12 months

Botulinum toxin A injections within the last 6 months

Therapeutic intervention targeting trunk control last 6 months

Surgery on lower limbs or trunk last 12 months

Trial population

Children with cerebral palsy presenting gait pattern disorders receive consultation and/or care (day or full hospitalization) at the Flavigny-sur-Moselle CMPRE.

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

270 Participants
are grouped into 2 trial groups
Group A: Children with cerebral palsy
Group B: Children with typical development

Trial outcomes

Primary outcomes

1

Trunk and center-of-mass accelerations and acceleration variability

In addition to the zeno walking track, inertial computers will be used to record accelerations of the patient's trunk and center of mass as they walk. One will be attached to the sternum, the other to the lumbosacral hinge, using hypoallergenic double-sided tape. A third will be attached to the patient's shoe to synchronize the data from the treadmill and the inertial units. Acceleration variability is calculated in post-processing.

Time frame
At the end of the one-day experimental

Secondary outcomes

1

Gait Variability Index

A composite score of gait variability based on spatio-temporal parameters, giving an index of gait regularity. The mean reference score is 100, and a score above 100 indicates that the patient is at least as stable as a patient from a healthy population.

Time frame
At the beginning of the one-day experimental
2

Trunk Control Measurement Scale score (TCMS)

The TCMS scale assesses trunk control in the seated position in three dimensions. The maximum (and best) score is 58 points, of which 20 correspond to static balance, 28 to selective movement control and 10 to the ability to perform dynamic extension movements.

Time frame
At the beginning of the one-day experimental
3

Early Clinical Assessment of Balance score

The Early Clinical Assessment of Balance is an evaluative measure used by clinicians to assess balance in the cerebral palsy population. Scoring is on a 0-100 scale where higher scores equate to better balance.

Time frame
At the beginning of the one-day experimental

Other outcomes

Sponsors and contacts

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