Antecolic Versus Retrocolic Gastrojejunostomy During Whipple's Procedure
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorUniversity of Thessaly
About this trial
Aim: This randomized clinical study aims to compare occurrence of DGE in patients undergoing either antecolic or retrocolic gastrojejunostomy following pancreaticoduodenectomy.
Methods: Participants of this study will be patients undergoing pylorus preserving pancreaticoduodenectomy at the Surgical Department of the University Hospital of Larissa. Patients will be randomized to undergo either an antecolic or a retrocolic gastrojejunostomy and the occurrence of DGE will then be compared between the two groups. Individuals younger than 18 or older than 75 years old, as well as patients who do not consent to participate in this trial, will be excluded.
Expected results: Based on available literature, antecolic gastrojejunostomy may be related with a lower incidence of DGE, without a statistically significant difference between the two methods. We aim to show if one of the two methods of gastrointestinal reconstruction (antecolic versus retrocolic) affects DGE.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age over 18 years old
Elective pancreaticoduodenectomy
Signed consent form
Disqualifiers
Age under 18 years old
Patients who are participants in other trials that may affect the results of this study
Patients who do not consent to participate in the study
Trial design
Design model
Single group
Treatments tested in this trial
Antecolic gastrojejunostomy
Procedure/SurgeryGastrojejunostomy in front of the transverse colon
Retrocolic gastrojejunostomy
Procedure/SurgeryGastrojejunostomy through the transverse mesocolon
Treatment groups
76 Participants
are divided into 2 treatment groupsGroup A: Antecolic gastrojejunostomyActive comparator 1 intervention
Group B: Retrocolic gastrojejunostomyActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Delayed Gastric Emptying
The occurence of delayed gastric emptying will be compared between two groups of patients: those who undergo an antecolic gastrojejunostomy and those who undergo a retrocolic approach.
Time frame
3 yearsSponsors and contacts
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Source ClinicalTrials.gov