Anterior Iliopsoas Muscle Space Block Versus Supra-iliac Anterior Quadratus Lumborum Block in Total Hip Arthroplasty

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-80
SponsorZagazig University

About this trial

Approximately 1.66 million hip fractures happen in a year worldwide. About 95% of these fractures happen in individuals older than 60 years. Surgical treatment involving THA is considered the best option for patients with hip fractures and those with degenerative changes in the hip joint, especially in the elderly, however, it is associated with moderate to severe postoperative pain.

Pain is one of the main factors limiting ambulation, increasing the risk of thromboembolism by immobility, and causing metabolic changes that affect other systems. Therefore, individualized pain management with the use of appropriate analgesia techniques is of paramount importance. Moreover, early intervention of rehabilitation aiming at a better postoperative recovery may reduce the length of hospital stay and return to daily. Effective pain management is one of the crucial components of enhanced recovery after surgery (ERAS).

Numerous regional anesthetic techniques have been used to provide analgesia following THA, including intrathecal morphine, epidural analgesia, fascia iliaca block, lumber plexus block, sacral plexus block, and local infiltration analgesia, however, each of these techniques has specific limitations that prevent them from being the analgesic technique of choice for THA.

Up to investigators' knowledge, there is no study done to compare the supra-iliac approach to the anterior QL block versus the Anterior iliopsoas muscle space block as pre-emptive analgesia in patients undergoing THA under general anesthesia

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patient acceptance.

Age 50-80 years old.

BMI ≤ 30 kg/m2

ASA I - III.

Disqualifiers

History of allergy to the LA agents used in this study

Skin lesion at the needle insertion site,

Those with bleeding disorders, sepsis, liver disease, and psychiatric disorders

Pre-existing neurological deficit in the lower extremity

Trial design

Design model

Parallel

Treatments tested in this trial

  • control

    Procedure/Surgery

    patient will be operated under general anesthesia

  • IPS

    Procedure/Surgery

    patients will receive ultrasound-guided anterior IPS block with 30 ml of bupivacaine 0.25% followed by general anesthesia.

  • Supra-iliac QL

    Procedure/Surgery

    patients will receive ultrasound-guided supra-iliac anterior QL block with 30 ml of bupivacaine 0.25% followed by general anesthesia.

Treatment groups

72 Participants
are divided into 3 treatment groups
Group A: control groupPlacebo comparator 1 intervention
Group B: IPS groupActive comparator 1 intervention
Group C: Supra-iliac QL groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

changes in Visual analogue scale (VAS)score

On a scale of 0-10, the patient will learn to quantify postoperative pain where 0= No pain and 10= Maximum worst pain

Time frame
measured at 1 hour, 3 hours,6 hours,12hours,18hours, 24 hours postoperatively

Secondary outcomes

1

Total dose of rescue analgesia

once the VAS score will be ≥ 3, rescue analgesia in the form of 1 μg/kg fentanyl will be given and the total dose consumed will be recorded

Time frame
in the first 24 hours postoperatively

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.