Health TrialsbyHealthPanel

Antipyretic Therapy With and Without Cold Sponging

ConditionFever
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-60
SponsorMuhammad Aamir Latif

About this trial

This study aims to fill the gaps regarding the effectiveness of paracetamol alone with paracetamol combined with cold sponging in febrile children.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Children of either gender

Aged 6 to 60 months.

Presenting with a fever (an axillary or oral temperature >38.0°C)

No use of paracetamol or other antipyretics within the past 6 hours. 4. Parental/guardian giving informed written consent.

Disqualifiers

Children with chronic systematic conditions (e.g., congenital heart defects, renal or respiratory diseases)

History of febrile seizures or other seizure disorders

Known hypersensitivity or contraindication to paracetamol

Presence of dermatological conditions that may aggravate by sponging (eg., eczema, contact dermatitis, psoriasis, skin infection, xerosis)

Trial design

Design model

Parallel

Treatments tested in this trial

  • Paracetamol

    Drug

    Children will receive paracetamol alone, as a single dose of paracetamol syrup (15 mg/kg) orally.

  • Paracetamol+Cold Sponging

    Combination product

    Children will receive paracetamol as a single dose of paracetamol syrup (15 mg/kg) orally, and cold sponging will be performed immediately following paracetamol administration for 15 minutes, using room-temperature water (approximately 25°C) to sponge the forehead, arms, and legs.

Treatment groups

210 Participants
are divided into 2 treatment groups
Group A: Paracetamol GroupExperimental treatment 1 intervention
Group B: Cold sponging GroupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Fever reduction

Achievement of a temperature \<38°C within 60 minutes will be considered as the reduction in fever and effectiveness of the treatment.

Time frame
60 minutes

Secondary outcomes

1

Change in heart rate

The change in the heart rate will be compared between the two groups.

Time frame
60 minutes
2

Change in respiratory rate

The change in the respiratory rate will be compared between the two groups.

Time frame
60 minutes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Muhammad Aamir Latif

Lead sponsor

RESnTEC, Institute of Research

Sponsor institution

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: