Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40+
SponsorXijing Hospital

About this trial

To observe the effect of different antithrombotic drugs on the prognosis of ischemic stroke patients with cerebral microbleeds. And further combined with proteomic methods to explore serological markers that can be used to accurately predict the prognosis of such patients.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients diagnosed clinically as ischemic stroke;

Age ≥ 40 years;

Onset time ≤ 3 months;

Informed consent was signed.

Disqualifiers

Patients with symptomatic intracranial hemorrhage;

bleeding lesion > 10 mm was found on SWI;

Vascular malformations, tumors, abscesses or other major non ischemic brain diseases were present;

There are contraindications for antithrombotic drugs use;

Trial population

The population we observed are hospitalized patients with new cerebral infarction and met the inclusion criteria(without exclusion criteria). The method of consecutive participant sampling is used to collect the included population.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Antithrombotic drugs

    Drug

    The purpose of our study is to observe the effect of various antithrombotic drugs on the prognosis of ischemic stroke patients with cerebral microbleeds.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Increase of cerebral microbleeds

How many cerebral microbleeds increased after 1 year of antithrombotic drugs treatment. The number of microbleeds will be detected by MR-SWI.

Time frame
1 year after onset

Secondary outcomes

1

Stroke recurrence rate

recurrence rate of ischemic stroke

Time frame
1 year after onset
2

The incidence of cerebral hemorrhage

Time frame
1 year after onset

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Xijing Hospital

Lead sponsor

Ankang Central Hospital

Collaborator

Yan'an University Affiliated Hospital

Collaborator