About this trial
To observe the effect of different antithrombotic drugs on the prognosis of ischemic stroke patients with cerebral microbleeds. And further combined with proteomic methods to explore serological markers that can be used to accurately predict the prognosis of such patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients diagnosed clinically as ischemic stroke;
Age ≥ 40 years;
Onset time ≤ 3 months;
Informed consent was signed.
Disqualifiers
Patients with symptomatic intracranial hemorrhage;
bleeding lesion > 10 mm was found on SWI;
Vascular malformations, tumors, abscesses or other major non ischemic brain diseases were present;
There are contraindications for antithrombotic drugs use;
Trial population
The population we observed are hospitalized patients with new cerebral infarction and met the inclusion criteria(without exclusion criteria). The method of consecutive participant sampling is used to collect the included population.
Trial design
Cohort
Prospective
Treatments tested in this trial
Antithrombotic drugs
DrugThe purpose of our study is to observe the effect of various antithrombotic drugs on the prognosis of ischemic stroke patients with cerebral microbleeds.
Treatment groups
Trial outcomes
Primary outcomes
Increase of cerebral microbleeds
How many cerebral microbleeds increased after 1 year of antithrombotic drugs treatment. The number of microbleeds will be detected by MR-SWI.
Secondary outcomes
Stroke recurrence rate
recurrence rate of ischemic stroke
The incidence of cerebral hemorrhage
Sponsors and contacts
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Xijing Hospital
Lead sponsor
Ankang Central Hospital
Collaborator
Yan'an University Affiliated Hospital
Collaborator