Health TrialsbyHealthPanel

Aortopathy Relationship To Imagery and Kinocardiography Features (ARTIK)

ConditionsAortic Valve DiseaseAortic Aneurysm
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversité Libre de Bruxelles

About this trial

Kinocardiography (KCG) is a portable measurement technique developed to estimate cardiac mechanical performance by studying the vibrations produced by myocardial contraction during each heartbeat and transmitted to the body surface.

The goal of this observational study is to learn about kinocardiography in patients with aortic valve disease (AVD) or thoracic aortic aneurysm (TAA). The investigators believe that this technology will enable to diagnose aortic valve disease and aortic aneurysm.

In patients with AVD of different severities or TAA, the investigators will collect informations from echocardiography and/or cardiac magnetic resonance imaging, KCG recordings, phonocardiography (PCG) recordings, and video recordings. Researchers will also compare subjects without any AVD nor TAA to better understand these effects on KCG, PCG and video signal.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

"Interventional treatment" group

Adults (>18 y)

Interventional treatment indication for severe AVD and/or severe TAA, as decided by the Heart Team

"Aortic valve disease of different severities" group

Disqualifiers

Any severe rhythm disorder such as frequent ventricular extrasystoles, atrial tachyarrhythmias

Subject's disabilty to give consent

Subjects suffering from aortic valve disease or thoracic aortic aneurysm will be excluded from the "control" group.

Trial population

Both inpatients and outpatients may be included in "interventional treatment" group and "aortic valve disease of different severities" group. "Control" group may include inpatients, outpatients and healthy subjects.

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • Kinocardiography

    Diagnostic test

    Technology Measuring Cardiac Mechanical Activity Via Accelerometers and Gyroscopes

Treatment groups

180 Participants
are divided into 3 treatment groups
Group A: Interventional treatment1 intervention
Group B: Aortic valve disease of different severities1 intervention
Group C: Control1 intervention

Trial outcomes

Primary outcomes

1

Understand and assess the complex mechanisms underlying the modifications of KCG signals in patients with AVD and/or TAA

Correlation between KCG parameters and imaging parameters (echocardiography, 4D flow MRI)

Time frame
12 months

Secondary outcomes

1

Comparing KCG to clinical assessment

Correlation between KCG parameters, phonocardiography, semiological signs and video signals

Time frame
18 months
2

Asses the clinical application of KCG to diagnose AVD and TAA

With a dedicated device and with a smartphone

Time frame
18 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Université Libre de Bruxelles

Lead sponsor

Erasme University Hospital

Sponsor institution

Erasme University Hospital

Collaborator

Source ClinicalTrials.gov
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