Application of 68GA-labeled CD73 Targeting Probe PET/CT Imaging in the Diagnosis of Malignant Tumor

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorPeking Union Medical College Hospital

About this trial

68Ga-DOTA-dPNE PET/CT imaging was performed on patients with malignant tumors to observe the binding of lesions with the tracer and evaluate the expression of CD73. At the same time, correlation analysis was performed combined with relevant clinical indicators to evaluate the efficacy of 68Ga-DOTA-dPNE in the diagnosis and guidance of malignant tumor patients, and predict the response of targeted therapy.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

1: Age: ≥18 years, expected survival ≥12 weeks 2: Without radiotherapy and chemotherapy, surgery or biopsy is feasible to obtain pathological diagnosis 3: Standard Solid Tumor Response Evaluation Criteria (RECIST) version 1.1 with at least one measurable target lesion 4: Obtain written informed consent and be able to follow up

Disqualifiers

None

Trial design

Design model

Single group

Treatments tested in this trial

  • 68GA-DOTA-dPNE

    Drug

    Intravenous administration of 68GA-DOTA-dPNE tracer

Treatment groups

50 Participants
are divided into 1 treatment group
Group A: Malignant tumorExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Lesion SUV value

Time frame
After the completion of the PET scan

Secondary outcomes

Other outcomes

Locations

1

Map coordinates are unavailable for these locations. Locations are shown below instead.

PUMCHRecruiting100730, Dongcheng, Beijing MunicipalityChinaChina

Sponsors and contacts

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