Application of DCE-MRI Based on 4D FreeBreathing in Predicting the Efficacy of Immune and Targeted Therapy in Lung Cancer

ConditionLung Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorYunnan Cancer Hospital

About this trial

This study aims to address the challenge of predicting the efficacy of targeted and immunotherapy in lung cancer patients. By utilizing two DCE-MRI images-one before treatment and one after one treatment cycle-along with the patients' clinical and pathological information, we aim to achieve accurate prediction of the therapeutic efficacy of targeted and immunotherapy in lung cancer patients.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Tumor size greater than 2 cm

Age between 18 and 75 years

Disqualifiers

Presence of MRI contraindications (e.g., metal implants, pacemaker implantation, etc.)

Allergy to gadolinium contrast agents

Lesions difficult to delineate on images due to conditions such as atelectasis or diffuse lesions

Trial design

Design model

Single group

Treatments tested in this trial

  • Application Value of MRI Imaging in Treatment Decision-Making for Lung Cancer

    Diagnostic test

    Chest MRI scans outside of the standard treatment protocol

Treatment groups

195 Participants
are divided into 1 treatment group
Group A: Application Value of MRI Imaging in Treatment Decision-Making for Lung CancerExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Tumor treatment response evaluation

This study aims to evaluate tumor treatment response using the RECIST V1.1 criteria, based on CT images taken within one week before treatment and two weeks after treatment completion.

Time frame
within one week before treatment and two weeks after treatment completion

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.