Application of Early Bundle Management of Mechanical Ventilation to Prevent Ventilator Dependence in Children

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age28-18
SponsorChildren's Hospital of Fudan University

About this trial

This study is based on the risk factors of previous studies to formulate a bundle treatment plan to prevent ventilator dependence in children, in order to reduce the proportion of ventilator dependence in children and provide a theoretical basis for reasonable intervention of children with mechanical ventilation.

Participants will receive intensive rehabilitation, nutrition, and tracheotomy at different time periods.

Researchers will compare the control group to see whether it can reduce the incidence of ventilator dependence

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Status epilepticus

Active intracranial hemorrhage

Intracranial hypertension

Unstable fracture of the spine

Trial design

Design model

Parallel

Treatments tested in this trial

  • early bedside rehabilitation

    Behavioral

    ① electrical diaphragm stimulation, ② electrical muscle stimulation, ③ passive limb movement, ④ respiratory rehabilitation.

  • nutrition program

    Dietary supplement

    (1) nutrition department consultation, (2) MDT to develop individualized nutritional pathways, nutrient formulations and use methods, and achieve the target nutritional level within 2 weeks

  • tracheotomy

    Procedure/Surgery

    early tracheotomy for special diseases (e.g central nervous system diseases) receiving mechanical ventilation 14-21 days recommended tracheotomy

Treatment groups

150 Participants
are divided into 2 treatment groups
Group A: intervention groupExperimental treatment 3 interventions
Group B: control groupNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

limb skeletal muscle function indexes

Skeletal muscle thickness and cross-sectional area were measured

Time frame
21 days after enrollment

Secondary outcomes

Other outcomes

Sponsors and contacts

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