Aquagenic Wrinkling Prediction
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-24
SponsorUniversity of Iowa
About this trial
The goal of this observational study is to determine whether an aquagenic wrinkling procedure (i.e., soaking hands in a water bath for up to 20 minutes) can be used as a screening tool for cystic fibrosis carrier status.
Participants will complete one visit where they will undergo an aquagenic wrinkling procedure to see how their hands respond.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Interested in participating in other CF Carrier-related research studies.
Disqualifiers
CF patient status
Unable to speak English
Unable to provide written informed consent
Prisoner status
Trial population
University students
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Aquagenic Wrinkling
Procedure/SurgeryParticipants will be asked to remove all jewelry from the hand(s) and wrist(s) that will be undergoing the aquagenic wrinkling procedures. Photographs will be taken of the palmar surface of the hand(s). The participant will submerge the hand(s) undergoing testing in a water bath for one minute. After one minute, they will remove their hand(s), dry them gently with a towel, and photographs will be taken of the palmar surface of the hand(s). The participant will re-submerge their hand(s) in the appropriate conditions for another minute and the process will be repeated 20 times for 20 total minutes submerged in the water.
Treatment groups
2,000 Participants
are divided into 2 treatment groupsGroup A: Potential Cystic Fibrosis Carriers1 intervention
Group B: Potential Controls1 intervention
Trial outcomes
Primary outcomes
1
Human Observation of Wrinkling
Photos of hands will be scored on a scale of 0 (no wrinkling) to 4 (severe wrinkling) at each minute by human observers.
Time frame
Up to 20 minutes2
Machine-Learning Observation of Wrinkling
Photos of hands will be scored by a machine-learning algorithm at each minute.
Time frame
Up to 20 minutesSponsors and contacts
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Source ClinicalTrials.gov