Arizona Alzheimer's Disease Research Center (ADRC)
ConditionAlzheimer Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40+
SponsorBanner Health
About this trial
The Arizona Alzheimer's Disease Research Center (ADRC) is the National Institute on Aging's (NIA's) first statewide AD Center (ADC), the only ADC in the Southwestern United States, and a leading example of statewide collaboration in biomedical research. It capitalizes on Arizona's strengths in brain imaging, genomics, computer science and biomathematics, the basic, cognitive and behavioral neurosciences, clinical, and neuropathological studies of AD, the discovery and evaluation of investigational treatments, and the study of normal cognitive aging.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Cognitively normal persons, individuals with mild cognitive impairment or dementia who are at least 40 years of age.
Willing to undergo health and cognitive assessments, and collection and banking of blood with venipuncture for genetic research, biomarker research, and DNA banking.
Disqualifiers
1. Participants whose diagnosis is unclear and confounded by multiple possible factors are excluded. Participants with diagnoses of non-AD dementias are not excluded.
Trial population
The Clinical Core maintains a target of 550 participants at all stages of the aging-dementia spectrum including 400 normal controls and 150 participants with MCI, probable AD dementia and other dementias. Embedded within these diagnostic categories are defined Latino and Native American cohorts. Participants will be referred to the ADRC from varying sources including, but not limited to, clinic referrals, community outreach programs, general advertising, national registries, and other sites within the consortium. Participants eligible for enrollment and those completing annual follow-up are discussed in frequent diagnostic consensus conferences. All undergo a standardized neuropsychological and neurological battery of tests at entry and annual tests at all sites.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Cognitive Status
The ADRC uses a prospective, standardized, and longitudinal clinical evaluation of participants to determine their cognitive status. This includes tests that assess short and long term memory, ability to complete daily tasks, and processing of information.
Time frame
12 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov