Arousal-related Memory Following Theta Burst Stimulation.
ConditionAnxiety
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorUniversity of Pennsylvania
About this trial
Aim 1: Active cTBS to IPS will disrupt arousal-dependent temporal memory, reflected in reduced relative order discrimination accuracy and expanded temporal distance estimates, relative to sham.
Aim 2: Active iTBS to IPS will enhance arousal-dependent temporal memory, reflected in improved relative order discrimination accuracy and compressed temporal distance estimates, relative to sham.
Aim 3: Baseline physiological arousal, trait anxiety (STAI), Beck Anxiety Inventory (BAI), trauma symptoms (PCL-5), and individualized E-field strength will predict the magnitude of TBS-induced behavioral changes in temporal memory.
Eligibility criteria
Qualifiers
Able to provide informed consent
Right-handed (to ensure consistency in motor threshold determination)
Disqualifiers
Non-English speaking
Significant medical problems
Current or past psychiatric disorder
Active or history of suicidal ideation
Trial design
Treatments tested in this trial
- Active TMS
- Sham TMS
Treatment groups
120 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov