Artificial Intelligence-Supported Digital Game and Exercise Applications in Children With Autism and Typically Developing Children

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-10
SponsorBurdur Mehmet Akif Ersoy University

About this trial

The goal of this study is to learn how artificial intelligence-supported digital games and exercise activities affect children with autism spectrum disorder and typically developing children aged 6 to 10 years. The main questions it aims to answer are:

Do the digital game and exercise activities improve children's motor skills? Do the activities affect repetitive behaviors, working memory, and brain activity?

Researchers will compare children who take part in the digital game and exercise activities with children who do not take part in these activities.

Participants will complete assessments before and after the study. Children in the intervention group will take part in artificial intelligence-supported digital game and exercise activities. Researchers will assess children's motor skills, working memory, behaviors, and brain activity.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Children aged 6-10 years.

Written informed consent from a parent or legal guardian.

Ability to understand and follow simple verbal instructions.

Ability to stand independently and perform basic locomotor movements.

Disqualifiers

Orthopedic surgery within the previous 6 months.

Presence of a neurological, orthopedic, or cardiovascular condition that may limit participation in movement-based activities.

An acute health condition that prevents participation in physical activity.

For typically developing participants: presence of a diagnosed neurodevelopmental disorder.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Movement-Based Digital Game Intervention

    Behavioral

    The intervention consists of a 10-week movement-based digital game program specifically developed for children aged 6-10 years. Participants in the intervention groups will attend two sessions per week, with each session lasting approximately 60 minutes. Sessions include warm-up, movement-based digital game activities, and cool-down. The digital games are delivered using an interactive projection system and require children to perform active body movements in response to visual and game-based tasks. Activities progressively target balance, coordination, locomotor skills, object control, hand-eye coordination, bilateral coordination, rhythm, reaching, jumping, changing direction, body awareness, and target-directed movements. Game difficulty and movement demands are progressively adjusted throughout the intervention period.

Treatment groups

60 Participants
are divided into 4 treatment groups
Group A: ASD Intervention GroupExperimental treatment 1 intervention
Group B: ASD Control GroupNo intervention 0 interventions
Group C: Typically Developing Intervention GroupExperimental treatment 1 intervention
Group D: Typically Developing Control GroupNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Motor Skill Performance

Motor proficiency in the 30 children with autism spectrum disorder and 30 typically developing children will be assessed using the Bruininks-Oseretsky Test of Motor Proficiency, Second Edition, Short Form (BOT-2 SF). The BOT-2 SF consists of 12 items representing eight motor skill areas: Fine Motor Precision, Fine Motor Integration, Manual Dexterity, Bilateral Coordination, Balance, Running Speed and Agility, Upper-Limb Coordination, and Strength. Raw performance scores for individual items are converted to point scores according to the BOT-2 scoring procedures and summed to obtain a Total Point Score. The BOT-2 SF Total Point Score ranges from 0 to 88. Higher scores indicate better overall motor proficiency, whereas lower scores indicate poorer motor proficiency.

Time frame
Baseline and immediately after the 10-week intervention
2

Repetitive Behaviors Assessed With the TEDÖ-R-TV

Repetitive behaviors in the 30 children with autism spectrum disorder will be assessed using the Repetitive Behavior Scale-Revised-Turkish Version (RBS-R-TV). The scale consists of 43 items covering six domains of repetitive behavior: Stereotyped Behavior, Self-Injurious Behavior, Compulsive Behavior, Ritualistic Behavior, Sameness Behavior, and Restricted Behavior. Each item is rated on a 4-point scale from 0 to 3. The total score ranges from 0 to 129. Higher scores indicate greater severity of repetitive behaviors and, therefore, a worse outcome, whereas lower scores indicate less severe repetitive behaviors.

Time frame
Baseline and immediately after the 10-week intervention
3

Working Memory Assessed With the Working Memory Scale (ÇBÖ)

Working memory will be assessed using the Working Memory Scale (ÇBÖ) developed by Ergül, Özgür-Yılmaz, and Demir. The Working Memory Scale for Children Aged 5-10 Years will be used to assess working memory performance in children with autism spectrum disorder and typically developing children. The scale consists of nine subtests grouped into four dimensions: Verbal Short-Term Memory (Digit Recall, Word Recall, and Nonword Recall), Visual Short-Term Memory (Pattern Matrix and Block Recall), Verbal Working Memory (Backward Digit Recall and First-Word Recall), and Visual Working Memory (Odd-One-Out and Spatial Discrimination). Each item includes two trials, and one point is awarded for each sequence correctly recalled or identified in the required order. The total raw score ranges from 0 to 86, with higher scores indicating better working memory performance.

Time frame
Baseline and immediately after the 10-week intervention
4

Brain Activity Assessed With Electroencephalography (EEG)

Brain activity will be assessed using electroencephalography (EEG) before and after the intervention. EEG recordings will be used to evaluate changes in brain activity associated with the artificial intelligence-supported digital game and exercise intervention.

Time frame
Baseline and immediately after the 10-week intervention

Secondary outcomes

Other outcomes

Sponsors and contacts

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